Phosphorylation of mpChREBP (Thr 666) at Ser(196) by mPKA

Stable Identifier
R-MMU-164055
Type
Reaction [transition]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Phosphorylation of mpChREBP (Thr 666) at Ser(196) by mPKA

Phosphorylation of ChREBP (Carbohydrate Response Element Binding Protein) at serine 196 by PKA inhibits its nuclear translocation. This reaction has been studied in detail using mouse proteins (Kawaguchi et al. 2001); the human version of the reaction is inferred from these studies.

Literature References
PubMed ID Title Journal Year
11698644 Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein

Kawaguchi, T, Takenoshita, M, Kabashima, T, Uyeda, K

Proc Natl Acad Sci U S A 2001
Participants
Catalyst Activity
Catalyst Activity
Title
cAMP-dependent protein kinase activity of Prkaca [cytosol]
Physical Entity
Activity
This event is regulated
Negatively by
Orthologous Events
Created
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