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Nuclear Pore Complex (NPC) [nuclear envelope]
Stable Identifier
R-MMU-157689
Type
Complex
Species
Mus musculus
Compartment
nuclear envelope
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Prophase (Mus musculus)
Nuclear Envelope Breakdown (Mus musculus)
Nuclear Pore Complex (NPC) Disassembly (Mus musculus)
CDK1 phosphorylates NUP98 (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to heat stress (Mus musculus)
Regulation of HSF1-mediated heat shock response (Mus musculus)
NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
Gene Silencing by RNA (Mus musculus)
Transcriptional regulation by small RNAs (Mus musculus)
Importin-8 imports AGO2:miRNA into the nucleus (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Metabolism (Mus musculus)
Metabolism of carbohydrates (Mus musculus)
Glucose metabolism (Mus musculus)
Glycolysis (Mus musculus)
Regulation of Glucokinase by Glucokinase Regulatory Protein (Mus musculus)
NPC transports GCK1:GKRP from cytosol to nucleoplasm (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Metabolism of RNA (Mus musculus)
Metabolism of non-coding RNA (Mus musculus)
snRNP Assembly (Mus musculus)
snRNP nuclear import and release (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Processing of Capped Intron-Containing Pre-mRNA (Mus musculus)
Transport of Mature Transcript to Cytoplasm (Mus musculus)
Transport of Mature mRNA derived from an Intron-Containing Transcript (Mus musculus)
Transport of the export-competent mRNP complex through the NPC (Mus musculus)
NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
mRNP complex dissociates from cytosolic face of NPC (Mus musculus)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Transport of Mature mRNAs Derived from Intronless Transcripts (Mus musculus)
Transport of Mature mRNA Derived from an Intronless Transcript (Mus musculus)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Transport of the SLBP Dependant Mature mRNA (Mus musculus)
Docking of Mature Replication Dependent Histone mRNA with the NPC (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Transport of the SLBP independent Mature mRNA (Mus musculus)
Docking of Mature Histone mRNA complex:TAP at the NPC (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Release of the SLBP independent Histone mRNA from the NPC (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
SUMOylation (Mus musculus)
SUMO E3 ligases SUMOylate target proteins (Mus musculus)
SUMOylation of DNA damage response and repair proteins (Mus musculus)
RANBP2 SUMOylates PML with SUMO1 (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
RANBP2 SUMOylates PML with SUMO2 (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
RANBP2 SUMOylates SP100 with SUMO1 (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
RANBP2 SUMOylates SP100 with SUMO2 (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
SUMOylation of RNA binding proteins (Mus musculus)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
SUMOylation of SUMOylation proteins (Mus musculus)
RANBP2 SUMOylates RANBP2 with SUMO1 (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
RANBP2 SUMOylates RANBP2 with SUMO2 (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
SUMOylation of chromatin organization proteins (Mus musculus)
RANBP2 SUMOylates HDAC4 with SUMO1 (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
RANBP2 SUMOylates HDAC4 with SUMO2,3 (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
SUMOylation of ubiquitinylation proteins (Mus musculus)
RANBP2 SUMOylates MDM2 with SUMO1 (Mus musculus)
Nuclear Pore Complex (NPC) [nuclear envelope] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 8
Aaas [nuclear envelope]
(Mus musculus)
x 32
Ndc1 [nuclear envelope]
(Mus musculus)
x 32
Nup107-160 complex [cytosol]
(Mus musculus)
x 8
Nup153 [nucleoplasm]
(Mus musculus)
x 16
Nup188 [nuclear envelope]
(Mus musculus)
x 16
Nup210 [nuclear envelope]
(Mus musculus)
x 8
Nup214 [cytosol]
(Mus musculus)
x 16
Nup42 [cytosol]
(Mus musculus)
x 32
Nup50 [nucleoplasm]
(Mus musculus)
x 32
Nup62 Complex [nuclear envelope]
(Mus musculus)
x 32
Nup88 [cytosol]
(Mus musculus)
x 32
Nup93 complex [nuclear envelope]
(Mus musculus)
x 8
Nup98 [nuclear envelope]
(Mus musculus)
x 16
Pom121 [nuclear envelope]
(Mus musculus)
x 48
Rae1 [nuclear envelope]
(Mus musculus)
x 8
Ranbp2 [cytosol]
(Mus musculus)
x 16
Seh1l [nuclear envelope]
(Mus musculus)
x 16
Tpr [nucleoplasm]
(Mus musculus)
Participates
as a component of
NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] (Mus musculus)
NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Mus musculus)
as an output of
mRNP complex dissociates from cytosolic face of NPC (Mus musculus)
as an input of
CDK1 phosphorylates NUP98 (Mus musculus)
This entity regulates
Positively
snRNP nuclear import and release
(Mus musculus)
Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC
(Mus musculus)
Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC
(Mus musculus)
Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC
(Mus musculus)
Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex
(Mus musculus)
Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC
(Mus musculus)
Docking of Mature Replication Dependent Histone mRNA with the NPC
(Mus musculus)
Release of the SLBP independent Histone mRNA from the NPC
(Mus musculus)
Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC
(Mus musculus)
Docking of Mature Histone mRNA complex:TAP at the NPC
(Mus musculus)
Transport of the export-competent mRNP complex through the NPC
(Mus musculus)
mRNP complex dissociates from cytosolic face of NPC
(Mus musculus)
Inferred From
Nuclear Pore Complex (NPC) [nuclear envelope]
(Homo sapiens)
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