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Bub3 [cytosol]
Stable Identifier
R-MMU-141416
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
BUB3, Q9WVA3
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
Mitotic Spindle Checkpoint (Mus musculus)
Amplification of signal from the kinetochores (Mus musculus)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Mus musculus)
MAD2 associates with the Mad1 kinetochore complex (Mus musculus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
MAD2 converted to an inhibitory state via interaction with Mad1 (Mus musculus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Mad1 binds kinetochore (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Release of activated MAD2 from kinetochores (Mus musculus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
Binding of the MCC complex to the APC/C complex (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Formation of the MCC complex (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Metaphase and Anaphase (Mus musculus)
Mitotic Anaphase (Mus musculus)
Separation of Sister Chromatids (Mus musculus)
ESPL1 (Separase) cleaves centromeric cohesin (Mus musculus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Separation of sister chromatids (Mus musculus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Mitotic Prometaphase (Mus musculus)
EML4 and NUDC in mitotic spindle formation (Mus musculus)
EML4 recruits NUDC to mitotic spindle (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Kinetochore capture of astral microtubules (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Resolution of Sister Chromatid Cohesion (Mus musculus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Mus musculus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Kinetochore assembly (Mus musculus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
PP2A-B56 dephosphorylates centromeric cohesin (Mus musculus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Phosphorylation of cohesin by PLK1 at centromeres (Mus musculus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Regulation of mitotic cell cycle (Mus musculus)
APC/C-mediated degradation of cell cycle proteins (Mus musculus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Mus musculus)
APC-Cdc20 mediated degradation of Nek2A (Mus musculus)
Association of Nek2A with MCC:APC/C (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Degradation of multiubiquitinated Nek2A (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Multiubiquitinated Nek2A [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Multiubiquitination of Nek2A (Mus musculus)
Multiubiquitinated Nek2A [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Mus musculus)
Association of Cyclin A with the APC/C (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Degradation multiubiquitinated Cyclin A (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
hBUBR1:hBUB3:MAD2* complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Regulation of APC/C activators between G1/S and early anaphase (Mus musculus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
Binding of the MCC complex to the APC/C complex (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Formation of the MCC complex (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases Activate Formins (Mus musculus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Mus musculus)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
CDC42:GTP recruits DIAPH2-2 to kinetochores (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
Bub3 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9WVA3
Gene Names
Bub3
Reference Genes
BioGPS Gene:12237 Bub3
ENSEMBL:ENSMUSG00000066979
ENSEMBL:ENSMUSG00000066979.7 Bub3
KEGG Gene (Mus musculus):12237 Bub3
Monarch:12237 Bub3
NCBI Gene:12237 Bub3
UCSC:Q9WVA3 Bub3
Reference Transcript
RefSeq:NM_001317350.1 Bub3
RefSeq:NM_009774.4 Bub3
Other Identifiers
101961_at
10558248
107128_at
12237
1416815_s_at
1448473_at
17484040
4318713
4353305
4472474
4484041
4626696
4631869
4650810
4954539
5311599
5426660
5545066
AA259399_s_at
A_51_P381873
A_52_P110040
GE1445391
GE35129
GO:0000278
GO:0000775
GO:0000776
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0007049
GO:0007059
GO:0007094
GO:0008608
GO:0022414
GO:0023052
GO:0033597
GO:0034501
GO:0043130
GO:0043226
GO:0051301
GO:0051321
GO:0051983
GO:0140014
GO:1990298
ILMN_2655944
Msa.5680.0_s_at
U67327_s_at
mMC003731
Participates
as a component of
hBUBR1:hBUB3:MAD2* complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
as an input of
Formation of the MCC complex (Mus musculus)
Inferred From
BUB3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001304279.1
,
NP_033904.2
Ensembl
ENSMUST00000084502
,
ENSMUSG00000066979
,
ENSMUSP00000081547
PRO
Q9WVA3
MGI
1343463
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