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Mad2l1 [cytosol]
Stable Identifier
R-MMU-141400
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
MAD2L1, Q9Z1B5
Locations in the PathwayBrowser for interactor UniProt:Q12834 CDC20
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
Mitotic Spindle Checkpoint (Mus musculus)
Amplification of signal from the kinetochores (Mus musculus)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Mus musculus)
MAD2 associates with the Mad1 kinetochore complex (Mus musculus)
Mad2l1 [cytosol] (Mus musculus)
Release of activated MAD2 from kinetochores (Mus musculus)
Mad2l1 [cytosol] (Mus musculus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)
Inactivation of APC/C via CDC20 sequestration (Mus musculus)
Mad2l1 [cytosol] (Mus musculus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
Formation of the MCC complex (Mus musculus)
Mad2l1 [cytosol] (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
Regulation of mitotic cell cycle (Mus musculus)
APC/C-mediated degradation of cell cycle proteins (Mus musculus)
Regulation of APC/C activators between G1/S and early anaphase (Mus musculus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)
Inactivation of APC/C via CDC20 sequestration (Mus musculus)
Mad2l1 [cytosol] (Mus musculus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
Formation of the MCC complex (Mus musculus)
Mad2l1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9Z1B5
Gene Names
Mad2l1
Reference Genes
BioGPS Gene:56150 Mad2l1
ENSEMBL:ENSMUSG00000029910
ENSEMBL:ENSMUSG00000029910.15 Mad2l1
KEGG Gene (Mus musculus):56150 Mad2l1
Monarch:56150 Mad2l1
NCBI Gene:56150 Mad2l1
UCSC:Q9Z1B5 Mad2l1
Reference Transcript
RefSeq:NM_019499.4 Mad2l1
RefSeq:XM_006506406.3 Mad2l1
Other Identifiers
10538832
1422460_at
1443171_at
17459236
4338670
4363305
4387851
4390752
4414369
4570053
4600802
4719085
4900800
4945233
5016489
5025250
5159807
5241538
5294245
5489074
5570726
56150
99632_at
A_51_P230873
A_52_P787579
A_55_P2133255
A_55_P2138333
A_55_P2179296
GE1420999
GE37394
GO:0000070
GO:0000132
GO:0000278
GO:0000775
GO:0000776
GO:0000922
GO:0005515
GO:0005634
GO:0005635
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0005856
GO:0007010
GO:0007049
GO:0007059
GO:0007094
GO:0007163
GO:0012501
GO:0023052
GO:0030163
GO:0033597
GO:0042177
GO:0042802
GO:0042803
GO:0043066
GO:0043226
GO:0044615
GO:0045841
GO:0045930
GO:0048471
GO:0051301
GO:0051660
GO:0072686
GO:0090267
GO:0140014
GO:1990728
ILMN_2776857
ILMN_2778872
mMC011883
Participates
as an input of
Inactivation of APC/C via CDC20 sequestration (Mus musculus)
Formation of the MCC complex (Mus musculus)
MAD2 associates with the Mad1 kinetochore complex (Mus musculus)
as a component of
MAD2*CDC20 complex [cytosol] (Mus musculus)
hBUBR1:hBUB3:MAD2* complex [cytosol] (Mus musculus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Mus musculus)
Mitotic checkpoint complex [cytosol] (Mus musculus)
as an output of
Release of activated MAD2 from kinetochores (Mus musculus)
Inferred From
Activated MAD2L1 [cytosol]
(Homo sapiens)
MAD2L1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_062372.2
,
XP_006506469.1
Ensembl
ENSMUSP00000098897
,
ENSMUSP00000112304
,
ENSMUST00000101343
,
ENSMUSG00000029910
,
ENSMUST00000116605
PRO
Q9Z1B5
MGI
1860374
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q12834 CDC20
3
CDC20 [cytosol]
(R-HSA-141412)
CDC20 [nucleoplasm]
(R-HSA-174112)
PolyUb-CDC20 [nucleoplasm]
(R-HSA-6783069)
0.564
2
UniProt:Q9Y6D9 MAD1L1
1
MAD1L1 [cytosol]
(R-HSA-141433)
0.564
2
UniProt:Q9UKK9 NUDT5
1
NUDT5 [cytosol]
(R-HSA-2393933)
0.564
2
UniProt:Q9Y448 SKAP
0.564
2
UniProt:P12270 TPR
5
TPR M489P [nucleoplasm]
(R-HSA-5661477)
TPR L458P [nucleoplasm]
(R-HSA-5661460)
TPR(2-629)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9711958)
TPR(2-629)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9711979)
TPR [nucleoplasm]
(R-HSA-157692)
0.564
2
UniProt:O60566 BUB1B
1
BUB1B [cytosol]
(R-HSA-141436)
0.564
2
UniProt:Q5JTV8 TOR1AIP1
1
TOR1AIP1 [cytosol]
(R-HSA-9715083)
0.564
2
UniProt:O95235 KIF20A
3
KIF20A [cytosol]
(R-HSA-1015868)
p-S528-KIF20A [nucleoplasm]
(R-HSA-156685)
KIF20A [nucleoplasm]
(R-HSA-156721)
0.564
2
UniProt:Q8N6N3 CA052
0.564
2
UniProt:Q7TSY8
1
Sgo2 [cytosol]
(R-MMU-376242)
0.508
3
UniProt:Q9NRI5 DISC1
0.499
2
UniProt:Q9JM97 Q9JM97
0.463
2
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