Reactome | Bax [cytosol]

Bax [cytosol]

Stable Identifier

R-MMU-139907

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

BAX activated, Q07813

Locations in the PathwayBrowser

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Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional Regulation by TP53 (Mus musculus)
      - TP53 Regulates Transcription of Cell Cycle Genes (Mus musculus)
        
        TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest (Mus musculus)
        
        SFN dimer binds BAX (Mus musculus)
        
        Bax [cytosol] (Mus musculus)
        
        SFN Dimer:BAX [cytosol] (Mus musculus)
        
        Bax [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q07813

Gene Names

Bax

Reference Genes

BioGPS Gene:12028 BAX

ENSEMBL:ENSMUSG00000003873

KEGG:mmu:12028 BAX

Monarch:12028 BAX

NCBI Gene:12028 BAX

UCSC:Q07813 BAX

Reference Transcript

RefSeq:NM_007527.3 BAX

Participates

as an input of

as a component of

as an output of

tBID activates BAX protein (Mus musculus)

Other forms of this molecule

Bax [mitochondrial outer membrane]

Inferred From

BAX [cytosol] (Homo sapiens)

BAX activated [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSMUST00000033093, ENSMUSP00000033093, ENSMUSG00000003873

PRO

Q07813

GlyGen

Q07813

MGI

99702

PDB

5W62, 2XA0

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P10417	1	Bcl2 [mitochondrial outer membrane] (R-MMU-50757)	0.573	2
UniProt:P21796 VDAC1	7	p-S65-Ub:VDAC1 [mitochondrial outer membrane] (R-HSA-9834991) K63polyUb-VDAC1 [mitochondrial outer membrane] (R-HSA-9834037) K48polyUb-VDAC1 [mitochondrial outer membrane] (R-HSA-5205624) Ub-VDAC1 [mitochondrial outer membrane] (R-HSA-9834989) VDAC1 [mitochondrial outer membrane] (R-HSA-1267988) VDAC1 [mitochondrial intermembrane space] (R-HSA-1267960) PolyUb-VDAC1 [mitochondrial outer membrane] (R-HSA-6783079)	0.544	2
UniProt:O75460 ERN1	2	ERN1 [endoplasmic reticulum membrane] (R-HSA-381076) p-S724-ERN1 [endoplasmic reticulum membrane] (R-HSA-381029)	0.524	2

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