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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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Psma1 [cytosol]
Stable Identifier
R-MMU-1236802
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Proteasome subunit alpha-6, PSA1_MOUSE
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
G1/S DNA Damage Checkpoints (Mus musculus)
p53-Dependent G1/S DNA damage checkpoint (Mus musculus)
p53-Dependent G1 DNA Damage Response (Mus musculus)
Stabilization of p53 (Mus musculus)
Autodegradation of the E3 ubiquitin ligase COP1 (Mus musculus)
Proteasome mediated degradation of COP1 (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
p53-Independent G1/S DNA damage checkpoint (Mus musculus)
p53-Independent DNA Damage Response (Mus musculus)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (Mus musculus)
Proteolytic degradation of ubiquitinated-Cdc25A (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
G2/M Checkpoints (Mus musculus)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Metaphase and Anaphase (Mus musculus)
Mitotic Anaphase (Mus musculus)
Separation of Sister Chromatids (Mus musculus)
Degradation of multiubiquitinated Securin (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Mitotic G2-G2/M phases (Mus musculus)
G2/M Transition (Mus musculus)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Mus musculus)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Proteasome-mediated degradation of PolyUb-FBXL7 (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
The role of GTSE1 in G2/M progression after G2 checkpoint (Mus musculus)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Regulation of mitotic cell cycle (Mus musculus)
APC/C-mediated degradation of cell cycle proteins (Mus musculus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Mus musculus)
Degradation of multiubiquitinated cell cycle proteins (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
APC/C:Cdc20 mediated degradation of Securin (Mus musculus)
Degradation of multiubiquitinated Securin (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Mus musculus)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Mus musculus)
Degradation multiubiquitinated Cyclin A (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
S Phase (Mus musculus)
Synthesis of DNA (Mus musculus)
Switching of origins to a post-replicative state (Mus musculus)
CDK-mediated phosphorylation and removal of Cdc6 (Mus musculus)
Ubiquitinated Cdc6 is degraded by the proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Orc1 removal from chromatin (Mus musculus)
Ubiquitinated Orc1 is degraded by the proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Ubiquitin-dependent degradation of Cyclin D (Mus musculus)
Proteasome mediated degradation of Cyclin D1 (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to chemical stress (Mus musculus)
KEAP1-NFE2L2 pathway (Mus musculus)
26S proteasome degrades Ub-NFE2L2 (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
ub UBXN7 is degraded by the 26S proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Cellular response to hypoxia (Mus musculus)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Mus musculus)
Proteasome proteolyzes ub-HIF-alpha (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
DNA Replication (Mus musculus)
Synthesis of DNA (Mus musculus)
Switching of origins to a post-replicative state (Mus musculus)
CDK-mediated phosphorylation and removal of Cdc6 (Mus musculus)
Ubiquitinated Cdc6 is degraded by the proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Orc1 removal from chromatin (Mus musculus)
Ubiquitinated Orc1 is degraded by the proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional regulation by RUNX1 (Mus musculus)
RUNX1 regulates transcription of genes involved in differentiation of HSCs (Mus musculus)
26S proteasome degrades TP73 polyubiquitinated by ITCH (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Class I MHC mediated antigen processing & presentation (Mus musculus)
Antigen processing-Cross presentation (Mus musculus)
Cross-presentation of soluble exogenous antigens (endosomes) (Mus musculus)
Proteasomal clevage of exogenous antigen (26S proteasome catalyst) (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Antigen processing: Ubiquitination & Proteasome degradation (Mus musculus)
Proteasomal cleavage of substrate (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Signaling by the B Cell Receptor (BCR) (Mus musculus)
Downstream signaling events of B Cell Receptor (BCR) (Mus musculus)
Activation of NF-kappaB in B cells (Mus musculus)
Ubiquitinated IkB is degraded (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
TCR signaling (Mus musculus)
Downstream TCR signaling (Mus musculus)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-1 family signaling (Mus musculus)
Interleukin-1 signaling (Mus musculus)
Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
TNFR2 non-canonical NF-kB pathway (Mus musculus)
26Sproteasome degrades K48polyUb-NIK (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
NIK-->noncanonical NF-kB signaling (Mus musculus)
26S proteasome processes p-7S-p100:RELB to form p52:RELB (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Protesomal degradation of K48polyUb-TRAF3 (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Innate Immune System (Mus musculus)
C-type lectin receptors (CLRs) (Mus musculus)
CLEC7A (Dectin-1) signaling (Mus musculus)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Dectin-1 mediated noncanonical NF-kB signaling (Mus musculus)
26S proteasome processes p-7S-p100:RELB to form p52:RELB (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Fc epsilon receptor (FCERI) signaling (Mus musculus)
FCERI mediated NF-kB activation (Mus musculus)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Metabolism of polyamines (Mus musculus)
Regulation of ornithine decarboxylase (ODC) (Mus musculus)
26S proteosome degrades ODC holoenzyme complex (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Metabolism of RNA (Mus musculus)
Regulation of mRNA stability by proteins that bind AU-rich elements (Mus musculus)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Mus musculus)
AUF1:mRNA complex is destroyed (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Deubiquitination (Mus musculus)
UCH proteinases (Mus musculus)
ADRM1 binds 26S proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
ADRM1:26S proteasome [cytosol] (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
ADRM1:26S proteaseome binds UCHL5 (Mus musculus)
ADRM1:26S proteasome [cytosol] (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
ADRM1:26S proteasome:UCHL5 [cytosol] (Mus musculus)
ADRM1:26S proteasome [cytosol] (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Ub-specific processing proteases (Mus musculus)
ADRM1:26S proteaseome binds USP14 (Mus musculus)
ADRM1:26S proteasome [cytosol] (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
ADRM1:26S proteasome:USP14 [cytosol] (Mus musculus)
ADRM1:26S proteasome [cytosol] (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Neddylation (Mus musculus)
26S proteasome degrades HIFalpha (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
26S proteasome degrades Ub-NFE2L2 (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
NEDD8,UBD:NUB1:26S proteasome [cytosol] (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
NEDD8 and UBD bind NUB1 and the 26S proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
NEDD8,UBD:NUB1:26S proteasome [cytosol] (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
ub UBXN7 is degraded by the 26S proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Proteasome assembly (Mus musculus)
Formation of the PA28-alpha-beta-20S proteasome (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
PA28-alpha-beta-20S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Formation of the PA28gamma-20S proteasome (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
PA28gamma-20S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Formation of the inner ring of the 20S core particle of the 26S proteasome (Mus musculus)
Half-proteasome [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
PSMG1:PSMG2:20S CP outer ring:POMP [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Formation of the inner ring of the 20S immunoproteasome core particle (Mus musculus)
Half-immunoproteasome [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
PSMG1:PSMG2:20S CP outer ring:POMP [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Formation of the inner ring of the 20S thymoproteasome core particle (Mus musculus)
Half-thymoproteasome [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
PSMG1:PSMG2:20S CP outer ring:POMP [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Formation of the outer ring of the 20S core particle (Mus musculus)
20S CP outer ring:PSMG3:PSMG4 [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Formation of the preholoproteasome (Mus musculus)
Half-proteasome [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Preholoproteasome [cytosol] (Mus musculus)
Half-proteasome [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Formation of the preholothymoproteasome (Mus musculus)
Half-thymoproteasome [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Preholothymoproteasome [cytosol] (Mus musculus)
Half-thymoproteasome [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Fromation of the preholoimmunoproteasome (Mus musculus)
Half-immunoproteasome [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Preholoimmunoproteasome [cytosol] (Mus musculus)
Half-immunoproteasome [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Maturation of the canonical 20S core particle (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Preholoproteasome [cytosol] (Mus musculus)
Half-proteasome [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
POMP binds the 20S core particle outer ring (Mus musculus)
PSMG1:PSMG2:20S CP outer ring:POMP [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
PSMG1:PSMG2:20S CP outer ring:PSMG3:PSMG4 [cytosol] (Mus musculus)
20S CP outer ring:PSMG3:PSMG4 [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
PSMG1:PSMG2 dimer binds the 20S core particle outer ring (Mus musculus)
20S CP outer ring:PSMG3:PSMG4 [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
PSMG1:PSMG2:20S CP outer ring:PSMG3:PSMG4 [cytosol] (Mus musculus)
20S CP outer ring:PSMG3:PSMG4 [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
PIP3 activates AKT signaling (Mus musculus)
PTEN Regulation (Mus musculus)
Regulation of PTEN stability and activity (Mus musculus)
Proteasome degrades polyubiquitinated PTEN (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF/MAP kinase cascade (Mus musculus)
Regulation of RAS by GAPs (Mus musculus)
NF1 is degraded by the proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
MAPK6/MAPK4 signaling (Mus musculus)
MAPK6 is degraded by the 26S proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Signaling by Hedgehog (Mus musculus)
Hedgehog 'off' state (Mus musculus)
Degradation of GLI1 by the proteasome (Mus musculus)
GLI1 is degraded by the proteasome after ubiquitination by ITCH (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
GLI3 is processed to GLI3R by the proteasome (Mus musculus)
GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Hedgehog 'on' state (Mus musculus)
ub-GLI is degraded by the proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Hedgehog ligand biogenesis (Mus musculus)
Hh C-terminal fragments are degraded by the proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Signaling by WNT (Mus musculus)
Beta-catenin independent WNT signaling (Mus musculus)
PCP/CE pathway (Mus musculus)
Asymmetric localization of PCP proteins (Mus musculus)
PRICKLE1 is degraded by the proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Degradation of beta-catenin by the destruction complex (Mus musculus)
Degradation of ubiquitinated beta catenin by the proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
TCF dependent signaling in response to WNT (Mus musculus)
Degradation of AXIN (Mus musculus)
Ub-RibC-AXIN is degraded by the proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Ubiquitinated AXIN is degraded by the proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Degradation of DVL (Mus musculus)
Ubiquitinated DVL is degraded by the proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Ubiquitinated DVL1 is degraded by the proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
Transport of small molecules (Mus musculus)
ABC-family proteins mediated transport (Mus musculus)
misfolded CFTR is degraded by the 26S proteasome (Mus musculus)
26S proteasome [cytosol] (Mus musculus)
20S core particle [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
Psma1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9R1P4 Psma1
Gene Names
Psma1
Chain
chain:1-263
Reference Genes
BioGPS Gene:26440 Psma1
KEGG:mmu:26440 Psma1
Monarch:26440 Psma1
NCBI Gene:26440 Psma1
UCSC:Q9R1P4 Psma1
Reference Transcript
RefSeq:NM_011965.2 Psma1
Other Identifiers
10338071
10338120
10338473
10338636
10338963
10338968
10338995
10339324
10339471
10339523
10339949
10340335
10340822
10340974
10341145
10341203
10341761
10341795
10341880
10341921
10342081
10342147
10342727
10342779
10342997
10343203
10343233
10343578
10343968
10344586
10567072
1415695_at
1458292_at
17203273
17203275
17203277
17203279
17203281
17203283
17203285
17203287
17203289
17203291
17203301
17203303
17203307
17203309
17203311
17203313
17203315
17203317
17203319
17203321
17495297
26440
4305781
4351594
4394024
4562191
4587412
4598072
4632918
4635862
4672402
4866189
4866258
4928983
4978708
5011969
5029464
5047991
5051391
5058925
5070373
5146925
5216178
5218375
5256013
5298516
5302789
5313087
5370909
5380370
5396884
5443593
5481895
5560099
5560216
5593705
5599443
5607129
96892_at
A_51_P469578
A_66_P117014
GE37220
GO:0000502
GO:0001530
GO:0002376
GO:0002862
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005839
GO:0006511
GO:0008289
GO:0010498
GO:0019773
GO:0030163
GO:0043161
GO:0043226
GO:0051603
ILMN_2777591
mMC010462
Participates
as a component of
m20S sCP outer ring [cytosol] (Mus musculus)
Proteasome [cytosol] (Mus musculus)
20S CP outer ring [cytosol] (Mus musculus)
as an input of
Formation of the outer ring of 20S core particle of mouse spermatoproteasome (Mus musculus)
Formation of the outer ring of the 20S core particle (Mus musculus)
Other forms of this molecule
Psma1 [nucleoplasm]
Inferred From
PSMA1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_036095.1
ENSEMBL
ENSMUST00000033008
,
ENSMUSP00000033008
PRO
Q9R1P4
GlyGen
Q9R1P4
MGI
1347005
PDB
3UNH
,
3UNF
,
3UNE
,
3UNB
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UM47 NOTCH3
20
Ub-NICD3 [cytosol]
(R-HSA-9021546)
Ub-NEXT3 [plasma membrane]
(R-HSA-9021545)
p-Y-NICD3 [cytosol]
(R-HSA-9018581)
Glc,GlcNAc-Fuc-Pre-NOTCH3 [Golgi membrane]
(R-HSA-1911429)
Glc,Gal-GlcNAc-Fuc-Pre-NOTCH3 [Golgi membrane]
(R-HSA-1911419)
NOTCH3(1572-2321) [Golgi membrane]
(R-HSA-156995)
14xGlcS-10xFucT-4xFucS-NOTCH3(40-1571) [Golgi membrane]
(R-HSA-1983672)
14xGlcS-10xFucT-4xFucS-NOTCH3(40-1571) [extracellular region]
(R-HSA-1983675)
NOTCH3(1572-2321) [plasma membrane]
(R-HSA-157231)
14xGlcS-10xFucT-4xFucS-NOTCH3(40-2321) [Golgi membrane]
(R-HSA-1472871)
14xGlcS-10xFucT-4xFucS-NOTCH3(40-2321) [endoplasmic reticulum membrane]
(R-HSA-1467307)
10xFucT-4xFucS-NOTCH3(40-2321) [endoplasmic reticulum membrane]
(R-HSA-1467382)
Pre-NOTCH3 [endoplasmic reticulum membrane]
(R-HSA-157102)
NICD3 [nucleoplasm]
(R-HSA-157928)
NICD3 [cytosol]
(R-HSA-157647)
NEXT3 [plasma membrane]
(R-HSA-157203)
NOTCH3(1629-1661) [plasma membrane]
(R-HSA-157657)
NOTCH3(40-1628) [extracellular region]
(R-HSA-157639)
FRINGE-modified NOTCH3 Extracellular fragment (NECD3) [Golgi membrane]
(R-HSA-1911522)
FRINGE-modified NOTCH3 Extracellular Fragment (NECD3) [plasma membrane]
(R-HSA-1911517)
0.508
2
UniProt:Q91X58 ZFN2B
0.499
2
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