Reactome | phospho-Ghr [plasma membrane]

phospho-Ghr [plasma membrane]

Stable Identifier

R-MMU-1169226

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

p-Y332,Y487,Y627-GHR(19-638), P16882

Locations in the PathwayBrowser

Expand all

Immune System (Mus musculus)

- Cytokine Signaling in Immune system (Mus musculus)
  - Growth hormone receptor signaling (Mus musculus)
    - PTP1B dephosphorylates GHR (Mus musculus)
      - Growth Hormone:p(Y332,487,627)-Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane] (Mus musculus)
        
        Growth Hormone:p(Y332,487,627)-Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Mus musculus)
        
        p(Y332,487,627)-Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Mus musculus)
        
        p(Y332,487,627)-Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Mus musculus)
        
        phospho-Ghr [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P16882 Ghr

Gene Names

Ghr

Chain

signal peptide:1-24, chain:25-650, chain:25-264

Reference Genes

BioGPS Gene:14600 Ghr

ENSEMBL:ENSMUSG00000055737 Ghr

KEGG Gene (Mus musculus):14600 Ghr

Monarch:14600 Ghr

NCBI Gene:14600 Ghr

UCSC:P16882 Ghr

Reference Transcript

Other Identifiers

10427402

1451501_a_at

14600

4334443

4353927

4607616

4858109

4970476

4993635

5194932

5372362

5503608

5535258

5553147

5580169

99108_s_at

A_52_P680935

A_55_P2059412

GE42624

GO:0000187

GO:0003674

GO:0004896

GO:0004903

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005737

GO:0005739

GO:0005829

GO:0005886

GO:0005887

GO:0006464

GO:0006790

GO:0006810

GO:0006897

GO:0007165

GO:0007259

GO:0008150

GO:0008219

GO:0009755

GO:0009897

GO:0009986

GO:0016020

GO:0016021

GO:0016192

GO:0017046

GO:0019221

GO:0019530

GO:0019838

GO:0019898

GO:0019899

GO:0019901

GO:0019903

GO:0019955

GO:0032355

GO:0032870

GO:0032991

GO:0036464

GO:0040007

GO:0040014

GO:0040018

GO:0042169

GO:0042445

GO:0042802

GO:0042803

GO:0042976

GO:0043025

GO:0043226

GO:0043235

GO:0044281

GO:0046427

GO:0048009

GO:0050731

GO:0060396

GO:0070195

GO:1901215

ILMN_3138922

Msa.27462.0_s_at

Participates

as a component of

p(Y332,487,627)-Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Mus musculus)

Other forms of this molecule

Growth hormone receptor binding protein [extracellular region]

Growth hormone receptor membrane-bound remnant [plasma membrane]

p-Y341,Y346,Y498,Y545,Y577,Y639-Ghr [plasma membrane]

phospho-Ghr [plasma membrane]

Activated growth hormone receptor [plasma membrane]

Ghr [extracellular region]

Ghr [plasma membrane]

Inferred From

p-Y332,Y487,Y627-GHR(19-638) [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 332 (in Homo sapiens)

Coordinate

332

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 487 (in Homo sapiens)

Coordinate

487

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 627 (in Homo sapiens)

Coordinate

627

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_001273299.1, NP_034414.2, NP_001041643.1

Ensembl

ENSMUSP00000106325, ENSMUSG00000055737, ENSMUST00000110697, ENSMUSP00000106326, ENSMUST00000110698

PRO

P16882

MGI

95708

GlyGen

P16882