Reactome | phospho-Ghr [plasma membrane]

phospho-Ghr [plasma membrane]

Stable Identifier

R-MMU-1169226

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

p-Y332,Y487,Y627-GHR(19-638), P16882

Locations in the PathwayBrowser

Expand all

Immune System (Mus musculus)

- Cytokine Signaling in Immune system (Mus musculus)
  - Growth hormone receptor signaling (Mus musculus)
    - PTP1B dephosphorylates GHR (Mus musculus)
      - Growth Hormone:p(Y332,487,627)-Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP2 [plasma membrane] (Mus musculus)
        
        Growth Hormone:p(Y332,487,627)-Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] (Mus musculus)
        
        p(Y332,487,627)-Growth Hormone Receptor:p(Y1007)-JAK2 dimer [plasma membrane] (Mus musculus)
        
        p(Y332,487,627)-Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Mus musculus)
        
        phospho-Ghr [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P16882 Ghr

Gene Names

Ghr

Chain

signal peptide:1-24, chain:25-650, chain:25-264

Reference Genes

BioGPS Gene:14600 Ghr

KEGG:mmu:14600 Ghr

Monarch:14600 Ghr

NCBI Gene:14600 Ghr

UCSC:P16882 Ghr

Reference Transcript

Other Identifiers

10427402

1417962_s_at

1451501_a_at

1451871_a_at

14600

17315635

4334443

4353927

4452391

4459984

4607616

4609350

4817409

4834507

4858109

4873220

4970476

4993635

5047787

5069944

5150974

5184847

5194932

5255957

5265637

5305349

5372362

5491640

5503608

5534107

5535258

5553147

5559484

5580169

5594991

5602990

99107_at

99108_s_at

A_51_P499854

A_52_P633550

A_52_P680935

A_52_P680941

A_55_P2059412

A_55_P2500473

GE1565954

GE42624

GO:0004896

GO:0004903

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005829

GO:0005886

GO:0006790

GO:0006897

GO:0007259

GO:0009629

GO:0009725

GO:0009755

GO:0009986

GO:0016020

GO:0016192

GO:0017046

GO:0019221

GO:0019530

GO:0019901

GO:0019903

GO:0032094

GO:0032107

GO:0032869

GO:0032870

GO:0034097

GO:0036464

GO:0040014

GO:0040018

GO:0042169

GO:0042445

GO:0042802

GO:0042803

GO:0043025

GO:0043226

GO:0043235

GO:0043434

GO:0045597

GO:0046427

GO:0048009

GO:0048856

GO:0051384

GO:0060089

GO:0060351

GO:0060396

GO:0060397

GO:0060416

GO:0070195

GO:0070555

ILMN_1247348

ILMN_1253504

ILMN_3138922

Msa.27462.0_s_at

m33324_s_at

mMC004673

Participates

as a component of

p(Y332,487,627)-Growth Hormone Receptor:p(Y1007)-JAK2 [plasma membrane] (Mus musculus)

Other forms of this molecule

Growth hormone receptor binding protein [extracellular region]

Growth hormone receptor membrane-bound remnant [plasma membrane]

p-Y341,Y346,Y498,Y545,Y577,Y639-Ghr [plasma membrane]

phospho-Ghr [plasma membrane]

Activated growth hormone receptor [plasma membrane]

Ghr [extracellular region]

Ghr [plasma membrane]

Inferred From

p-Y332,Y487,Y627-GHR(19-638) [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 332 (in Homo sapiens)

Coordinate

332

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 487 (in Homo sapiens)

Coordinate

487

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 627 (in Homo sapiens)

Coordinate

627

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_001041643.1, NP_034414.2, NP_001273299.1

ENSEMBL

ENSMUST00000110698, ENSMUSP00000106326, ENSMUST00000110697, ENSMUSP00000106325, ENSMUSG00000055737

PRO

P16882

GlyGen

P16882

MGI

95708