Reactome | CBL [cytosol]

CBL [cytosol]

Stable Identifier

R-MMU-112199

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

P22682

Locations in the PathwayBrowser for interactor UniProt:P13379 CD5

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External Reference Information

External Reference

UniProt:P22682 Cbl

Gene Names

Cbl

Chain

chain:1-913

Reference Genes

BioGPS Gene:12402 Cbl

ENSEMBL:ENSMUSG00000034342.10 Cbl

KEGG Gene (Mus musculus):12402 Cbl

Monarch:12402 Cbl

NCBI Gene:12402 Cbl

UCSC:P22682 Cbl

Reference Transcript

RefSeq:NM_007619.2 Cbl

Other Identifiers

100291_at

10592734

116969_at

12402

1434829_at

1450457_at

1455886_at

17526130

4361862

4403536

4415417

4420368

4508041

4593724

4598445

4633693

4740321

4741176

4809000

4814464

4883602

4980486

4993737

5023099

5027471

5035380

5036985

5038915

5080629

5095709

5143702

5306058

5336414

5377256

5386113

5386244

5398407

5408432

5421993

5430525

5515408

5526809

5557574

5575005

99092_at

A_52_P153939

A_52_P819011

A_55_P2070174

A_55_P2800298

GE1548980

GE34815

GO:0000209

GO:0001784

GO:0002376

GO:0003824

GO:0004842

GO:0005509

GO:0005515

GO:0005737

GO:0005794

GO:0005829

GO:0005886

GO:0005925

GO:0005929

GO:0006468

GO:0006511

GO:0006513

GO:0006974

GO:0007165

GO:0007166

GO:0008152

GO:0008584

GO:0010332

GO:0012501

GO:0014823

GO:0016020

GO:0016192

GO:0016567

GO:0016600

GO:0016740

GO:0017124

GO:0019901

GO:0022414

GO:0023051

GO:0023052

GO:0030163

GO:0030424

GO:0030426

GO:0030971

GO:0032487

GO:0033574

GO:0036120

GO:0036211

GO:0036312

GO:0042059

GO:0042594

GO:0042995

GO:0043066

GO:0043226

GO:0043303

GO:0045121

GO:0045453

GO:0045471

GO:0046872

GO:0046875

GO:0048260

GO:0048471

GO:0048856

GO:0051865

GO:0051897

GO:0061630

GO:0070086

GO:0071456

GO:0140096

GO:1990090

GO:1990782

GO:2000583

ILMN_2649011

Msa.2194.0_at

mMC017603

Participates

as an input of

as a component of

as a candidate of

CBL:GRB2,CBL [cytosol] (Mus musculus)

as an output of

Other forms of this molecule

Cbl [cytosol]

p-Y-Cbl [cytosol]

phospho-p-Y-CBL [cytosol]

phospho-p-Y371-CBL [cytosol]

phospho-p-Y371-CBL [plasma membrane]

phospho-PolyUb,p-Y700,Y731,Y774-CBL [cytosol]

phospho-p-Y700,Y731,Y774-CBL [cytosol]

Inferred From

CBL [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_031645.2

IntEnz

2.3.2.27

Ensembl

ENSMUSP00000146244, ENSMUST00000206720, ENSMUSG00000034342

PRO

P22682

MGI

88279

PDB

2D9S

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q60631 Grb2	3	Grb2 [cytosol] (R-MMU-74686) Grb2 [plasma membrane] (R-MMU-202993) Grb2 [cytosol] (R-MMU-443287)	0.643	7
UniProt:P39688 Fyn	6	Fyn [cytosol] (R-MMU-420333) phospho-MyrG-p-Y420-FYN-1 [plasma membrane] (R-MMU-9032530) pFyn (420) [cytosol] (R-MMU-420335) pFyn(Y531) [cytosol] (R-MMU-420350) phospho-p-S21,Y420-FYN [cytosol] (R-MMU-5218745) MyrG,p-Y420-Fyn [plasma membrane] (R-MMU-9037733)	0.564	5
UniProt:Q9JLQ0 Cd2ap	1	CD2AP_MOUSE [cytosol] (R-MMU-451711)	0.547	5
UniProt:Q6Q899 Rigi	4	PolyUb-DDX58 [cytosol] (R-MMU-6782770) Rig-I [cytosol] (R-MMU-936468) K63polyUb-DDX58 [cytosol] (R-MMU-918191) DDX58 [cytosol] (R-MMU-168917)	0.537	3
UniProt:Q3U1F9	2	Pag1 [plasma membrane] (R-MMU-180500) phospho-Pag1 [plasma membrane] (R-MMU-180494)	0.499	2
UniProt:P13379 CD5			0.499	5
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.499	2
UniProt:Q01279	6	phospho-p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-MMU-8869138) phospho-p-4Y-EGFR [plasma membrane] (R-MMU-180287) phospho-p-Y1016,Y1069,Y1092,Y1110,Y1197-EGFR [plasma membrane] (R-MMU-8864019) EGFR [plasma membrane] (R-MMU-179837) phospho-p-Y1086,Y1101-EGFR [plasma membrane] (R-MMU-179868) phospho-p-6Y-EGFR [plasma membrane] (R-MMU-179803)	0.499	2

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