Reactome | PML [nucleoplasm]

PML [nucleoplasm]

Stable Identifier

R-MMU-1031706

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

Q60953

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q60953

Reference Genes

BioGPS Gene:18854 Q8BSJ6

ENSEMBL:ENSMUSG00000036986

KEGG:mmu:18854 Q8BSJ6

Monarch:18854 Q8BSJ6

NCBI Gene:18854 Q8BSJ6

UCSC:Q60953 PML

Reference Transcript

Participates

as a member of

PML,TRIM27,PIAS1,2-1 [nucleoplasm] (Mus musculus)

as an input of

as a component of

This entity regulates

Negatively

USP7 deubiquitinates monoubiquitinated PTEN (Mus musculus)

Other forms of this molecule

polySUMO3-K65,K160,K490-PML [nucleoplasm]

polySUMO2-K65,K160,K490-PML [nucleoplasm]

monoSUMO1-K65,160,490-PML [nucleoplasm]

Inferred From

PML [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_032910.3, NP_835188.2, NP_001298017.1

ENSEMBL

ENSMUST00000114136, ENSMUSG00000036986, ENSMUST00000085673, ENSMUSP00000109771, ENSMUSP00000082816

PRO

Q60953

GlyGen

Q60953

MGI

104662

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8UN00 Q8UN00			0.65	4
UniProt:Q60979 Q60979			0.556	5
UniProt:Q16236 NFE2L2	13	p-S40-NFE2L2 [nucleoplasm] (R-HSA-9715109) p-S,T-NFE2L2 [nucleoplasm] (R-HSA-9715110) p-S40-NFE2L2 [cytosol] (R-HSA-8932290) p-S,T-NFE2L2 [cytosol] (R-HSA-8932311) NFE2L2 [cytosol] (R-HSA-201566) p-S,T-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760033) p-S40-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760018) ub-NFE2L2 [cytosol] (R-HSA-9758077) ub-p-S335, S338,T-NFE2L2 [nucleoplasm] (R-HSA-9762055) ub-p-S40, S335, S338- NFE2L2 [nucleoplasm] (R-HSA-9762058) p-S344, S347,T-NFE2L2 [nucleoplasm] (R-HSA-9762048) p-S40, S344, S347- NFE2L2 [nucleoplasm] (R-HSA-9762050) p-S,T,S558-NFE2L2 [nucleoplasm] (R-HSA-9795736)	0.544	2
UniProt:O54943 Per2	6	Ub-K,p-7S-Per2 [cytosol] (R-MMU-9932499) phospho-Per2 [cytosol] (R-MMU-9932526) p-6S-Per2 [nucleoplasm] (R-MMU-9920666) p-7S-Per2 [cytosol] (R-MMU-9920656) p-S394-Per2 [cytosol] (R-MMU-9920685) Per2 [cytosol] (R-MMU-508621)	0.463	4

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