Reactome | PHF21A [nucleoplasm]

PHF21A [nucleoplasm]

Stable Identifier

R-HSA-996754

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

PHD finger protein 21A, BHC80, PF21A_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - Potential therapeutics for SARS (Homo sapiens)
        
        HDAC1:2-containing complex binds HDAC2 Inhibitors (Homo sapiens)
        
        HDAC1:2-containing complex [nucleoplasm] (Homo sapiens)
        
        BHC complex [nucleoplasm] (Homo sapiens)
        
        PHF21A [nucleoplasm] (Homo sapiens)
        
        HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Homo sapiens)
        
        HDAC1:2-containing complex [nucleoplasm] (Homo sapiens)
        
        BHC complex [nucleoplasm] (Homo sapiens)
        
        PHF21A [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q96BD5 PHF21A

Gene Names

PHF21A, BHC80, KIAA1696, BM-006

Chain

chain:1-680

Reference Genes

BioGPS Gene:51317 PHF21A

COSMIC (genes):PHF21A PHF21A

CTD Gene:51317 PHF21A

dbSNP Gene:51317 PHF21A

ENSEMBL:ENSG00000135365 PHF21A

ENSEMBL_homo_sapiens_GENE:ENSG00000135365.17 PHF21A

HGNC:24156 PHF21A

KEGG Gene (Homo sapiens):51317 PHF21A

Monarch:51317 PHF21A

NCBI Gene:51317 PHF21A

OMIM:608325 PHF21A

UCSC:Q96BD5 PHF21A

Reference Transcript

Other Identifiers

11720589_s_at

11720590_a_at

11720591_a_at

11748061_a_at

1554153_PM_a_at

1554153_a_at

16737669

203278_PM_s_at

203278_s_at

227090_PM_at

227090_at

3371338

3371340

3371341

3371342

3371343

3371348

3371349

3371351

3371354

3371357

3371360

3371361

3371363

3371368

3371369

3371371

3371372

3371377

3371378

3371401

3371403

3371405

3371406

3371409

3371412

3371417

3371418

3371422

3371423

3371424

3371425

3371426

39551_at

51317

63326_at

7947624

A_23_P202715

A_23_P359015

A_24_P41524

A_33_P3346473

GE54964

GE88325

GO:0000118

GO:0000122

GO:0003677

GO:0003682

GO:0005515

GO:0005634

GO:0005654

GO:0006325

GO:0006351

GO:0006355

GO:0043226

GO:0046872

GO:1990391

HMNXSV003036653

HMNXSV003052380

Hs.104888.0.S1_3p_at

Hs2.106826.2.S1_3p_s_at

ILMN_1699496

PH_hs_0022262

TC11001716.hg

g7706159_3p_a_at

Participates

as a component of

BHC complex [nucleoplasm] (Homo sapiens)

Inferred To

PHF21A [nucleoplasm] (Bos taurus)

PHF21A [nucleoplasm] (Canis familiaris)

PHF21A [nucleoplasm] (Gallus gallus)

PHF21A [nucleoplasm] (Sus scrofa)

Ghost homologue of PHF21A [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of PHF21A [nucleoplasm] (Xenopus tropicalis)

Phf21a [nucleoplasm] (Mus musculus)

Phf21a [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

XP_011518475.1, XP_016873380.1, XP_005253022.1, NP_001095272.1, XP_011518481.1, NP_057705.3, XP_011518476.1

OpenTargets

ENSG00000135365

GeneCards

Q96BD5

HPA

ENSG00000135365-PHF21A

Ensembl

ENST00000690620, ENSP00000502222, ENST00000323180, ENST00000676320, ENST00000418153, ENSG00000135365, ENSP00000398824, ENSP00000323152, ENSP00000508589

PRO

Q96BD5

Pharos - Targets

Q96BD5

Orphanet

21296

PDB

2PUY, 2YQL

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N9N5 BANP	1	BANP [nucleoplasm] (R-HSA-3221973)	0.666	4
UniProt:Q13077 TRAF1	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.666	4
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.556	3
UniProt:Q02447 SP3	3	monoSUMO1-K551-SP3 [nucleoplasm] (R-HSA-3247472) polySUMO2-K551-SP3 [nucleoplasm] (R-HSA-6804456) SP3 [nucleoplasm] (R-HSA-2160951)	0.556	3
UniProt:Q92769 HDAC2	2	monoSUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958) HDAC2 [nucleoplasm] (R-HSA-205135)	0.527	2