MITF-M binds the CDC25B gene

Stable Identifier
R-HSA-9926488
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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MITF-M binds the CDC25B gene
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
MITF-M binds to an E-box element at +83 of the CDC25B 5' untranslated region (UTR) to upregulate expression as assessed by ChIP and RNA seq (Strub et al, 2011).
Literature References
PubMed ID Title Journal Year
21258399 Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma

Strub, T, Giuliano, S, Ye, T, Bonet, C, Keime, C, Kobi, D, Le Gras, S, Cormont, M, Ballotti, R, Bertolotto, C, Davidson, I

Oncogene 2011
Participants
Input
Output
Participates
as an event of
Authored
Vu, HN  (2024-11-05)
Steingrímsson, E  (2024-11-05)
Reviewed
Vu, HN  (2024-11-05)
Steingrímsson, E  (2024-11-05)
Created
Rothfels, K  (2024-11-01)
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