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p-S90-BMAL1:p-T451,T461-CLOCK:RORA gene [nucleoplasm]
Stable Identifier
R-HSA-9923020
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Circadian clock (Homo sapiens)
Phosphorylated BMAL1:CLOCK (ARNTL:CLOCK) activates expression of core clock genes (Homo sapiens)
Phosphorylated BMAL1:CLOCK positively regulates expression of RORA (Homo sapiens)
p-S90-BMAL1:p-T451,T461-CLOCK:RORA gene [nucleoplasm] (Homo sapiens)
p-S90-BMAL1:p-T451,T461-CLOCK binds the RORA gene (Homo sapiens)
p-S90-BMAL1:p-T451,T461-CLOCK:RORA gene [nucleoplasm] (Homo sapiens)
Phosphorylation of CLOCK, acetylation of BMAL1 (ARNTL) at target gene promoters (Homo sapiens)
p-T451,T461-CLOCK is phosphorylated on serines-440,441,446 (Homo sapiens)
p-S90-BMAL1:p-T451,T461-CLOCK:target gene [nucleoplasm] (Homo sapiens)
p-S90-BMAL1:p-T451,T461-CLOCK:RORA gene [nucleoplasm] (Homo sapiens)
Participants
components
p-S90-BMAL1:p-T451,T461-CLOCK [nucleoplasm]
(Homo sapiens)
RORA gene [nucleoplasm]
(Homo sapiens)
Participates
as a member of
p-S90-BMAL1:p-T451,T461-CLOCK:target gene [nucleoplasm] (Homo sapiens)
as an output of
p-S90-BMAL1:p-T451,T461-CLOCK binds the RORA gene (Homo sapiens)
This entity regulates
Positively
Phosphorylated BMAL1:CLOCK positively regulates expression of RORA
(Homo sapiens)
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