Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
19S RP Lid Module 1 [nucleoplasm]
Stable Identifier
R-HSA-9918360
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G1/S Transition (Homo sapiens)
Cyclin E associated events during G1/S transition (Homo sapiens)
SCF(Skp2)-mediated degradation of p27/p21 (Homo sapiens)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Homo sapiens)
26S proteasome [nucleoplasm] (Homo sapiens)
19S regulatory particle [nucleoplasm] (Homo sapiens)
19S RP lid [nucleoplasm] (Homo sapiens)
19S RP lid particle 2 [nucleoplasm] (Homo sapiens)
19S RP Lid Module 1 [nucleoplasm] (Homo sapiens)
Regulation of mitotic cell cycle (Homo sapiens)
APC/C-mediated degradation of cell cycle proteins (Homo sapiens)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Homo sapiens)
APC/C:Cdh1-mediated degradation of Skp2 (Homo sapiens)
26S proteasome [nucleoplasm] (Homo sapiens)
19S regulatory particle [nucleoplasm] (Homo sapiens)
19S RP lid [nucleoplasm] (Homo sapiens)
19S RP lid particle 2 [nucleoplasm] (Homo sapiens)
19S RP Lid Module 1 [nucleoplasm] (Homo sapiens)
Autodegradation of Cdh1 by Cdh1:APC/C (Homo sapiens)
Degradation of multiubiquitinated Cdh1 (Homo sapiens)
26S proteasome [nucleoplasm] (Homo sapiens)
19S regulatory particle [nucleoplasm] (Homo sapiens)
19S RP lid [nucleoplasm] (Homo sapiens)
19S RP lid particle 2 [nucleoplasm] (Homo sapiens)
19S RP Lid Module 1 [nucleoplasm] (Homo sapiens)
S Phase (Homo sapiens)
Cyclin A:Cdk2-associated events at S phase entry (Homo sapiens)
SCF(Skp2)-mediated degradation of p27/p21 (Homo sapiens)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Homo sapiens)
26S proteasome [nucleoplasm] (Homo sapiens)
19S regulatory particle [nucleoplasm] (Homo sapiens)
19S RP lid [nucleoplasm] (Homo sapiens)
19S RP lid particle 2 [nucleoplasm] (Homo sapiens)
19S RP Lid Module 1 [nucleoplasm] (Homo sapiens)
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
KEAP1-NFE2L2 pathway (Homo sapiens)
Nuclear events mediated by NFE2L2 (Homo sapiens)
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 (Homo sapiens)
Ub,pS335,S338,T NFE2L2 is degraded (Homo sapiens)
26S proteasome [nucleoplasm] (Homo sapiens)
19S regulatory particle [nucleoplasm] (Homo sapiens)
19S RP lid [nucleoplasm] (Homo sapiens)
19S RP lid particle 2 [nucleoplasm] (Homo sapiens)
19S RP Lid Module 1 [nucleoplasm] (Homo sapiens)
Circadian clock (Homo sapiens)
Degradation of CRY and PER proteins (Homo sapiens)
Proteolysis of K48polyUb,p-S-CRY1,2 (Homo sapiens)
26S proteasome [nucleoplasm] (Homo sapiens)
19S regulatory particle [nucleoplasm] (Homo sapiens)
19S RP lid [nucleoplasm] (Homo sapiens)
19S RP lid particle 2 [nucleoplasm] (Homo sapiens)
19S RP Lid Module 1 [nucleoplasm] (Homo sapiens)
DNA Replication (Homo sapiens)
DNA Replication Pre-Initiation (Homo sapiens)
Assembly of the pre-replicative complex (Homo sapiens)
Ubiquitinated geminin is degraded by the proteasome (Homo sapiens)
26S proteasome [nucleoplasm] (Homo sapiens)
19S regulatory particle [nucleoplasm] (Homo sapiens)
19S RP lid [nucleoplasm] (Homo sapiens)
19S RP lid particle 2 [nucleoplasm] (Homo sapiens)
19S RP Lid Module 1 [nucleoplasm] (Homo sapiens)
Developmental Biology (Homo sapiens)
Gastrulation (Homo sapiens)
Formation of paraxial mesoderm (Homo sapiens)
Somitogenesis (Homo sapiens)
RIPPLY2 binds TBX6 and recruits the 26S proteasome (Homo sapiens)
26S proteasome [nucleoplasm] (Homo sapiens)
19S regulatory particle [nucleoplasm] (Homo sapiens)
19S RP lid [nucleoplasm] (Homo sapiens)
19S RP lid particle 2 [nucleoplasm] (Homo sapiens)
19S RP Lid Module 1 [nucleoplasm] (Homo sapiens)
TBX6:RIPPLY2:26S proteasome [nucleoplasm] (Homo sapiens)
26S proteasome [nucleoplasm] (Homo sapiens)
19S regulatory particle [nucleoplasm] (Homo sapiens)
19S RP lid [nucleoplasm] (Homo sapiens)
19S RP lid particle 2 [nucleoplasm] (Homo sapiens)
19S RP Lid Module 1 [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX2 (Homo sapiens)
Regulation of RUNX2 expression and activity (Homo sapiens)
26S proteasome degrades PolyUb-RUNX2 (Homo sapiens)
26S proteasome [nucleoplasm] (Homo sapiens)
19S regulatory particle [nucleoplasm] (Homo sapiens)
19S RP lid [nucleoplasm] (Homo sapiens)
19S RP lid particle 2 [nucleoplasm] (Homo sapiens)
19S RP Lid Module 1 [nucleoplasm] (Homo sapiens)
Transcriptional regulation by RUNX3 (Homo sapiens)
Regulation of RUNX3 expression and activity (Homo sapiens)
Polyubiquitinated RUNX3 is degraded by the proteasome (Homo sapiens)
26S proteasome [nucleoplasm] (Homo sapiens)
19S regulatory particle [nucleoplasm] (Homo sapiens)
19S RP lid [nucleoplasm] (Homo sapiens)
19S RP lid particle 2 [nucleoplasm] (Homo sapiens)
19S RP Lid Module 1 [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Hedgehog (Homo sapiens)
Hedgehog 'on' state (Homo sapiens)
GLI2,3 are degraded by the proteasome (Homo sapiens)
26S proteasome [nucleoplasm] (Homo sapiens)
19S regulatory particle [nucleoplasm] (Homo sapiens)
19S RP lid [nucleoplasm] (Homo sapiens)
19S RP lid particle 2 [nucleoplasm] (Homo sapiens)
19S RP Lid Module 1 [nucleoplasm] (Homo sapiens)
Signaling by NOTCH (Homo sapiens)
Signaling by NOTCH4 (Homo sapiens)
Negative regulation of NOTCH4 signaling (Homo sapiens)
Proteasome degrades ubiquitinated NICD4 (Homo sapiens)
26S proteasome [nucleoplasm] (Homo sapiens)
19S regulatory particle [nucleoplasm] (Homo sapiens)
19S RP lid [nucleoplasm] (Homo sapiens)
19S RP lid particle 2 [nucleoplasm] (Homo sapiens)
19S RP Lid Module 1 [nucleoplasm] (Homo sapiens)
Participants
components
PSMD11 [nucleoplasm]
(Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [nucleoplasm]
(Homo sapiens)
Participates
as a component of
19S RP lid particle 2 [nucleoplasm] (Homo sapiens)
Inferred To
19S RP Lid Module 1 [nucleoplasm]
(Bos taurus)
19S RP Lid Module 1 [nucleoplasm]
(Caenorhabditis elegans)
19S RP Lid Module 1 [nucleoplasm]
(Canis familiaris)
19S RP Lid Module 1 [nucleoplasm]
(Danio rerio)
19S RP Lid Module 1 [nucleoplasm]
(Dictyostelium discoideum)
19S RP Lid Module 1 [nucleoplasm]
(Drosophila melanogaster)
19S RP Lid Module 1 [nucleoplasm]
(Gallus gallus)
19S RP Lid Module 1 [nucleoplasm]
(Mus musculus)
19S RP Lid Module 1 [nucleoplasm]
(Rattus norvegicus)
19S RP Lid Module 1 [nucleoplasm]
(Sus scrofa)
19S RP Lid Module 1 [nucleoplasm]
(Xenopus tropicalis)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
