Poly(rC) binding protein 2 (PCB2), is one of the negative regulators of RIG-I/MDA5 signaling. It interacts with MAVS/IPS-1 and mediates its ubiquitin/proteasomal degradation by recruiting E3 ligase AIP4/ITCHY.
Sun, W, Jiang, Z, You, F, Liang, S, Sun, H, Zhai, Z, Zhou, X
© 2023 Reactome