Poly(rC) binding protein 2 (PCB2), is one of the negative regulators of RIG-I/MDA5 signaling. It interacts with MAVS/IPS-1 and mediates its ubiquitin/proteasomal degradation by recruiting E3 ligase AIP4/ITCHY.
You, F, Sun, H, Zhou, X, Sun, W, Liang, S, Zhai, Z, Jiang, Z
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