Reactome | KIFC1 [cytosol]

KIFC1 [cytosol]

Stable Identifier

R-HSA-990500

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Kinesin-like protein KIFC1, KIFC1_HUMAN, HSET

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
    - Golgi-to-ER retrograde transport (Homo sapiens)
      - COPI-dependent Golgi-to-ER retrograde traffic (Homo sapiens)
        
        Retrograde COPI vesicles bind kinesin and microtubules (Homo sapiens)
        
        Kinesins:microtubule [cytosol] (Homo sapiens)
        
        Kinesins [cytosol] (Homo sapiens)
        
        Kinesin-14 [cytosol] (Homo sapiens)
        
        KIFC1 [cytosol] (Homo sapiens)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Homo sapiens)
        
        Kinesins:microtubule [cytosol] (Homo sapiens)
        
        Kinesins [cytosol] (Homo sapiens)
        
        Kinesin-14 [cytosol] (Homo sapiens)
        
        KIFC1 [cytosol] (Homo sapiens)
        
        Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Homo sapiens)
        
        Kinesins:microtubule [cytosol] (Homo sapiens)
        
        Kinesins [cytosol] (Homo sapiens)
        
        Kinesin-14 [cytosol] (Homo sapiens)
        
        KIFC1 [cytosol] (Homo sapiens)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Homo sapiens)
        
        Kinesins:microtubule [cytosol] (Homo sapiens)
        
        Kinesins [cytosol] (Homo sapiens)
        
        Kinesin-14 [cytosol] (Homo sapiens)
        
        KIFC1 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9BW19 KIFC1

Gene Names

KIFC1, HSET, KNSL2

Chain

chain:1-673

Reference Genes

BioGPS Gene:3833 KIFC1

COSMIC (genes):KIFC1 KIFC1

CTD Gene:3833 KIFC1

dbSNP Gene:3833 KIFC1

ENSEMBL:ENSG00000237649 KIFC1

ENSEMBL_homo_sapiens_GENE:ENSG00000204197.9 KIFC1

ENSEMBL_homo_sapiens_GENE:ENSG00000233450.7 KIFC1

ENSEMBL_homo_sapiens_GENE:ENSG00000237649.8 KIFC1

HGNC:6389 KIFC1

KEGG Gene (Homo sapiens):3833 KIFC1

Monarch:3833 KIFC1

NCBI Gene:3833 KIFC1

OMIM:603763 KIFC1

UCSC:Q9BW19 KIFC1

Reference Transcript

RefSeq:NM_002263.3 KIFC1

Other Identifiers

11724209_a_at

17007459

17036071

17038792

17041352

209680_PM_s_at

209680_s_at

2903648

2903649

2903650

2903654

2903655

2903656

2903657

2903658

2903659

2903661

2903662

2903663

2903667

2903668

2903669

348_at

349_g_at

3833

38933_at

8118669

8179564

A_23_P133956

D14678_at

GE56053

GO:0000070

GO:0000166

GO:0000278

GO:0003774

GO:0003777

GO:0003824

GO:0005524

GO:0005634

GO:0005737

GO:0005768

GO:0005769

GO:0005813

GO:0005815

GO:0005819

GO:0005856

GO:0005871

GO:0005874

GO:0007010

GO:0007018

GO:0007049

GO:0007059

GO:0007080

GO:0008017

GO:0008092

GO:0016020

GO:0016787

GO:0016887

GO:0031410

GO:0043226

GO:0051301

GO:0072686

GO:0090307

GO:0140014

GO:0140657

HMNXSV003035289

ILMN_2222008

PH_hs_0001793

TC06000421.hg

TC6_mcf_hap5000095.hg

TC6_qbl_hap6000101.hg

TC6_ssto_hap7000090.hg

g12653842_3p_a_at

Participates

as a component of

Kinesin-14 [cytosol] (Homo sapiens)

as an input of

Kinesin-14 is a dimer (Homo sapiens)

Inferred To

KIFC1 [cytosol] (Caenorhabditis elegans)

KIFC1 [cytosol] (Danio rerio)

KIFC1 [cytosol] (Mus musculus)

KIFC1 [cytosol] (Plasmodium falciparum)

KIFC1 [cytosol] (Rattus norvegicus)

KIFC1 [cytosol] (Schizosaccharomyces pombe)

KIFC1 [cytosol] (Sus scrofa)

Homologues of KIFC1 [cytosol] (Mus musculus)

Cross References

RefSeq

NP_002254.2

OpenTargets

ENSG00000237649

HPA

ENSG00000237649-KIFC1

ZINC - Substances

KIFC1_HUMAN

GeneCards

Q9BW19

ZINC target

Q9BW19

Ensembl

ENSP00000363647, ENSP00000393963, ENSG00000237649, ENST00000448818, ENSG00000204197, ENSG00000233450, ENSP00000407885, ENST00000374523, ENST00000428849

PRO

Q9BW19

Pharos - Targets

Q9BW19

ZINC - Predictions - Purchasable

KIFC1_HUMAN

HMDB Protein

HMDBP10766

PDB

5WDH