MIR27B microRNA binds 3'UTR of TGFBR3 mRNA

Stable Identifier
R-HSA-9860139
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
3/5
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MIR27B microRNA binds 3'UTR of TGFBR3 mRNA
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Dual luciferase assay indicates that miR‐27b‐3p significantly reduced the luciferase activity by binding to the site of 1525‐1531 of TGFBR3 3ʹ‐UTR suggesting that TGFBR3 is a target of miR‐27b‐3p (Yang et al, 2019)
Literature References
PubMed ID Title Journal Year
30729664 Novel role of the clustered miR-23b-3p and miR-27b-3p in enhanced expression of fibrosis-associated genes by targeting TGFBR3 in atrial fibroblasts

Yang, Z, Xiao, Z, Guo, H, Fang, X, Liang, J, Zhu, J, Yang, J, Li, H, Pan, R, Yuan, S, Dong, W, Zheng, XL, Wu, S, Shan, Z

J Cell Mol Med 2019
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Authored
Tiwari, K  (2023-07-25)
Created
Tiwari, K  (2024-01-31)
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