Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
DGAT2 gene [nucleoplasm]
Stable Identifier
R-HSA-9859276
Type
DNA Sequence [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Epigenetic regulation by WDR5-containing histone modifying complexes (Homo sapiens)
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Homo sapiens)
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Homo sapiens)
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Homo sapiens)
Coactivators are recruited to liganded PPARG:RXRA heterodimer (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:DGAT2 gene:nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:Ligand-bound RXRA:DGAT2 gene:nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
Corepressors are released from liganded PPARG:RXRA heterodimer (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:DGAT2 gene:nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:Ligand-bound RXRA:DGAT2 gene:nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
DGAT2 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)
Activated PPARG:RXRA:DGAT2 gene:H3K4me1-Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
DGAT2 gene:H3K4me1-nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
MLL4-ASCOM, (MLL3-ASCOM) complex monomethylates nucleosomes at PPARG:RXRA-bound enhancers (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:H3K4me1-Nucleosomes:MLL4,(MLL3)-ASCOM (active chromatin state) [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:DGAT2 gene:H3K4me1-Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
DGAT2 gene:H3K4me1-nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:MLL4,(MLL3)-ASCOM:DGAT2 gene:nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
MLL4-ASCOM,(MLL3-ASCOM) complex is recruited to ligand- and coactivator-bound PPARG:RXRA heterodimer (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:DGAT2 gene:nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes:MLL4,(MLL3)-ASCOM [nucleoplasm] (Homo sapiens)
Activated PPARG:RXRA:MLL4,(MLL3)-ASCOM:DGAT2 gene:nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
PPARG binds ligands (Homo sapiens)
PPARG ligands:PPARG:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:RXRA:NCoR/SMRT:DGAT2 gene:nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA:NCoR/SMRT:adipogenesis genes:Nucleosomes (repressive chromatin state) [nucleoplasm] (Homo sapiens)
PPARG:RXRA:NCoR/SMRT:DGAT2 gene:nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA heterodimer binds target gene loci (Homo sapiens)
Adipogenesis target genes of PPARG and MLL3/4:Nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA:Adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
PPARG:RXRA:DGAT2 gene:nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
RXRA binds ligands (Homo sapiens)
PPARG ligands:PPARG:RXRA ligands:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:Ligand-bound RXRA:NCoR/SMRT:DGAT2 gene:nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
PPARG ligands:PPARG:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
Ligand-bound PPARG:RXRA:NCoR/SMRT:DGAT2 gene:nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci (Homo sapiens)
PPARG:RXRA:Adipogenesis genes:Nucleosomes [nucleoplasm] (Homo sapiens)
PPARG:RXRA:DGAT2 gene:nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
PPARG:RXRA:NCoR/SMRT:adipogenesis genes:Nucleosomes (repressive chromatin state) [nucleoplasm] (Homo sapiens)
PPARG:RXRA:NCoR/SMRT:DGAT2 gene:nucleosomes [nucleoplasm] (Homo sapiens)
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
ENSEMBL:ENSG00000062282 DGAT2
Gene Names
DGAT2, HMFN1045, UNQ738/PRO1433
Participates
as a component of
DGAT2 gene:Nucleosome [nucleoplasm] (Homo sapiens)
DGAT2 gene:H3K4me1-nucleosomes [nucleoplasm] (Homo sapiens)
as an input of
DGAT2 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)
Inferred To
Ghost homologue of DGAT2 gene [nucleoplasm]
(Bos taurus)
Ghost homologue of DGAT2 gene [nucleoplasm]
(Canis familiaris)
Ghost homologue of DGAT2 gene [nucleoplasm]
(Danio rerio)
Ghost homologue of DGAT2 gene [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of DGAT2 gene [nucleoplasm]
(Gallus gallus)
Ghost homologue of DGAT2 gene [nucleoplasm]
(Mus musculus)
Ghost homologue of DGAT2 gene [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of DGAT2 gene [nucleoplasm]
(Sus scrofa)
© 2025
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
