MITF-M dimer binds the CCNB1 gene

Stable Identifier
R-HSA-9858643
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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MITF-M binds the promoter of the G2/mitotic cyclin CCNB1 as assessed by ChIP in melanoma cells, and treatment of these cells with anti-MITF siRNA reduces protein levels of CCNB1 (Strub et al, 2011).
Literature References
PubMed ID Title Journal Year
21258399 Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma

Ye, T, Cormont, M, Keime, C, Kobi, D, Davidson, I, Le Gras, S, Giuliano, S, Bonet, C, Bertolotto, C, Ballotti, R, Strub, T

Oncogene 2011
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