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L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm]
Stable Identifier
R-HSA-9856821
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Regulation of endogenous retroelements (Homo sapiens)
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex (Homo sapiens)
MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
MPHOSPH8 of the HUSH complex bound to retroelement chromatin binds ZCCHC8 of the NEXT complex (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
NEXT complex:HUSH complex:L1HS:L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Homo sapiens)
me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
me3-K16-ATF7IP:SETDB1 and MORC2 bind MPHOSPH8 (MPP8) in HUSH complex:L1HS,L1PA2,3 heterochromatin (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
Participants
components
L1HS,L1PA2,3 [nucleoplasm]
(Homo sapiens)
Nucleosome with H3K9me3 [nucleoplasm]
(Homo sapiens)
Participates
as a component of
NEXT complex:HUSH complex:L1HS:L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
as an input of
MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin (Homo sapiens)
Inferred To
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm]
(Bos taurus)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm]
(Canis familiaris)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm]
(Danio rerio)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm]
(Gallus gallus)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm]
(Rattus norvegicus)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm]
(Sus scrofa)
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