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L1HS,L1PA2,3 [nucleoplasm]
Stable Identifier
R-HSA-9856819
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Regulation of endogenous retroelements (Homo sapiens)
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex (Homo sapiens)
MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
MPHOSPH8 of the HUSH complex bound to retroelement chromatin binds ZCCHC8 of the NEXT complex (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
NEXT complex:HUSH complex:L1HS:L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Homo sapiens)
me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
me3-K16-ATF7IP:SETDB1 and MORC2 bind MPHOSPH8 (MPP8) in HUSH complex:L1HS,L1PA2,3 heterochromatin (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
Participants
members
L1HS [nucleoplasm]
(Homo sapiens)
L1PA2 [nucleoplasm]
(Homo sapiens)
L1PA3 [nucleoplasm]
(Homo sapiens)
Participates
as a component of
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
Inferred To
Ghost homologue of L1HS,L1PA2,3 [nucleoplasm]
(Bos taurus)
Ghost homologue of L1HS,L1PA2,3 [nucleoplasm]
(Canis familiaris)
Ghost homologue of L1HS,L1PA2,3 [nucleoplasm]
(Danio rerio)
Ghost homologue of L1HS,L1PA2,3 [nucleoplasm]
(Gallus gallus)
Ghost homologue of L1HS,L1PA2,3 [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of L1HS,L1PA2,3 [nucleoplasm]
(Sus scrofa)
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