Reactome | STARD7 transports Q10 to plasma membrane

STARD7 transports Q10 to plasma membrane

Stable Identifier

R-HSA-9856510

Type

Reaction [transition]

Species

Homo sapiens

Compartment

plasma membrane, mitochondrial outer membrane

ReviewStatus

5/5

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STARD7 transports Q10 to plasma membrane

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Cytosolic STARD7 is a lipid carrier that is required for transport of Q10H2 between inner and outer mitochondrial membranes. This isoform results from cleavage of further 12 amino acids from the miochondrial isoform (Deshwal et al., 2023; reviewed in Guile et al., 2023).

Literature References

PubMed ID	Title	Journal	Year
36658222	Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7 Lemke, K, Tatsuta, T, Deshwal, S, Cors, E, Bartsch, T, Onishi, M, Nolte, H, Langer, T, Giavalisco, P, Ried, K	Nat Cell Biol	2023
37507930	New Insights on the Uptake and Trafficking of Coenzyme Q Guile, MD, Jain, A, Clarke, CF, Anderson, KA	Antioxidants (Basel)	2023