Reactome | COQ8B [mitochondrial inner membrane]

COQ8B [mitochondrial inner membrane]

Stable Identifier

R-HSA-9856289

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

ADCK4

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96D53 COQ8B

Gene Names

COQ8B, ADCK4

Chain

chain:1-544

Reference Genes

BioGPS Gene:79934 COQ8B

COSMIC (genes):COQ8B COQ8B

CTD Gene:79934 COQ8B

dbSNP Gene:79934 COQ8B

ENSEMBL:ENSG00000123815 COQ8B

HGNC:19041 COQ8B

KEGG:hsa:79934 COQ8B

Monarch:79934 COQ8B

NCBI Gene:79934 COQ8B

OMIM:615567 COQ8B

UCSC:Q96D53 COQ8B

Reference Transcript

Other Identifiers

11755559_a_at

16872472

16872489

220434_3p_at

220434_PM_at

220434_at

227324_PM_at

227324_at

242609_PM_x_at

242609_x_at

3862729

3862730

3862731

3862732

3862733

3862734

3862735

3862736

3862737

3862739

3862740

3862741

3862742

3862743

3862744

3862745

3862747

3862748

3862749

3862750

3862751

3862752

3862753

3862754

3862755

3862756

3862757

3862758

3862759

3862760

3862761

3862762

3862763

3862764

3862765

3862766

3862768

3862769

3862770

3862771

3862772

3862773

3862774

3862775

3862776

3862782

51393_at

79934

8036938

8036954

A_23_P208400

A_24_P16592

GE54457

GE656646

GE82979

GO:0003824

GO:0005524

GO:0005737

GO:0005739

GO:0005829

GO:0005886

GO:0006744

GO:0008289

GO:0016301

GO:0016740

GO:0016787

GO:0016887

GO:0021692

GO:0031966

GO:0043226

HMNXSV003006823

Hs.130712.0.S1_3p_at

Hs.230980.0.A1_3p_at

Hs.230980.0.A1_3p_x_at

ILMN_1700349

PH_hs_0007709

TC19001544.hg

TC19001545.hg

g13376315_3p_at

Participates

as a member of

COQ8A,B [mitochondrial inner membrane] (Homo sapiens)

Inferred To

Q6AY19 [mitochondrial inner membrane] (Rattus norvegicus)

P27697 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

Q54IH6 [mitochondrial inner membrane] (Dictyostelium discoideum)

A3QJU3 [mitochondrial inner membrane] (Danio rerio)

COQ8B [mitochondrial inner membrane] (Sus scrofa)

Coq8 [mitochondrial inner membrane] (Drosophila melanogaster)

Q18486 [mitochondrial inner membrane] (Caenorhabditis elegans)

Q566J8 [mitochondrial inner membrane] (Mus musculus)

A0A3Q1LK03 [mitochondrial inner membrane] (Bos taurus)

abc1 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_079152.3, NP_001136027.1

ZINC - World Drugs

ADCK4_HUMAN

Guide to Pharmacology - Targets

1928

OpenTargets

ENSG00000123815

ENSEMBL

ENST00000594720, ENSP00000315118, ENST00000678404, ENSP00000243583, ENST00000243583, ENST00000677018, ENST00000679130, ENST00000678467, ENST00000324464, ENST00000601967, ENSP00000503480, ENST00000678419, ENSP00000504085, ENSP00000470876, ENSP00000504072, ENSP00000470916, ENSP00000504845, ENSP00000503944

ZINC - FDA approved

ADCK4_HUMAN

ZINC - Substances

ADCK4_HUMAN

ZINC target

Q96D53

ZINC - Biogenic

ADCK4_HUMAN

PRO

Q96D53

ZINC - Investigational

ADCK4_HUMAN

HPA

ENSG00000123815-COQ8B

Pharos - Targets

Q96D53

ZINC - Predictions - Purchasable

ADCK4_HUMAN

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC5 M	10	M [plasma membrane] (R-COV-9755780) N-glycan M [virion membrane] (R-COV-9694385) M [virion membrane] (R-COV-9694320) M [endocytic vesicle membrane] (R-COV-9694563) N-glycan M [endocytic vesicle membrane] (R-COV-9694738) M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694439) N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694446) M [endoplasmic reticulum membrane] (R-COV-9767620) nascent M [endoplasmic reticulum lumen] (R-COV-9694279) N-glycan M [endoplasmic reticulum membrane] (R-COV-9694684)	0.643	3