MITF-M-dependent CEACAM1 expression

Stable Identifier
R-HSA-9856061
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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CEACAM1 is a cell adhesion molecule that contributes to melanoma by influencing invasion and metastasis (reviewed in Goding and Arnheiter, 2019; Turcu et al 2016; Smart et al, 2021). CEACAM1 is a direct target of MITF-M as assessed by ChIP (Ullrich et al, 2015; Strub et al, 2011).
Literature References
PubMed ID Title Journal Year
26301891 MITF is a critical regulator of the carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in malignant melanoma

Ullrich, N, Davidson, I, Sánchez-Del-Campo, L, Breitenbuecher, F, Horn, S, Zhao, F, Schadendorf, D, Goding, CR, Löffek, S, Helfrich, I, Singer, BB, Ennen, M

Pigment Cell Melanoma Res 2015
27642217 CEACAM1: Expression and Role in Melanocyte Transformation

Turcu, G, Jilaveanu, LB, Zurac, SA, Ion, DA, Cioplea, MD, Nedelcu, RI, Brînzea, A

Dis Markers 2016
21258399 Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma

Ye, T, Cormont, M, Keime, C, Kobi, D, Davidson, I, Le Gras, S, Giuliano, S, Bonet, C, Bertolotto, C, Ballotti, R, Strub, T

Oncogene 2011
31123060 MITF-the first 25 years

Arnheiter, H, Goding, CR

Genes Dev 2019
33004622 Cell Adhesion Molecules in Plasticity and Metastasis

Smart, JA, Hartsough, EJ, Oleksak, JE

Mol Cancer Res 2021
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