Kinesin-8 is a dimer

Stable Identifier
R-HSA-984609
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Kinesin-8 is a plus-end-directed dimeric kinesin with an internal motor domain (Loughlin et al. 2008) that can depolymerize stable microtubuless specifically at their plus-ends (Pereira et al. 1997) in a length-dependent manner (Varga et al. 2006). Human kinesin-8 KIF18A is believed to promote chromosome congression by attenuating chromosome oscillation magnitudes (Stumpff et al. 2008).

Literature References
PubMed ID Title Journal Year
17346968 The human kinesin Kif18A is a motile microtubule depolymerase essential for chromosome congression

Mayr, MI, Hümmer, S, Bormann, J, Grüner, T, Adio, S, Woehlke, G, Mayer, TU

Curr Biol 2007
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