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Glycosphingolipid transport
Stable Identifier
R-HSA-9845576
Type
Pathway
Species
Homo sapiens
Compartment
cytosol
,
endoplasmic reticulum membrane
,
Golgi membrane
,
plasma membrane
ReviewStatus
5/5
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Transport of small molecules (Homo sapiens)
Glycosphingolipid transport (Homo sapiens)
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After biosynthesis on the Golgi membrane, gangliosides localize to other membranes via vesicle transport, endocytosis, and exocytosis. To decouple transport from vesicular transport of proteins, gangliosides are additionally transported via non-vesicular processes (reviewed by Perry & Ridgway, 2005; Funato et al., 2020).
Literature References
PubMed ID
Title
Journal
Year
31054928
Vesicular and non-vesicular lipid export from the ER to the secretory pathway
Muñiz, M
,
Riezman, H
,
Funato, K
Biochim Biophys Acta Mol Cell Biol Lipids
2020
15907394
Molecular mechanisms and regulation of ceramide transport
Ridgway, ND
,
Perry, RJ
Biochim Biophys Acta
2005
Participants
Events
Vesicles transport GSL from Golgi to plasma membrane
(Homo sapiens)
PLEKHA8 catalyzes transport of GlcCer to plasma membrane
(Homo sapiens)
CLN3 transports GalCer to plasma membrane
(Homo sapiens)
GLTP transports GSL from plasma membrane to ER membrane
(Homo sapiens)
CPTP transports C1P from plasma membrane to Golgi membrane
(Homo sapiens)
ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane
(Homo sapiens)
Participates
as an event of
Transport of small molecules (Homo sapiens)
Event Information
Go Biological Process
ceramide transport (0035627)
Orthologous Events
Glycosphingolipid transport (Bos taurus)
Glycosphingolipid transport (Caenorhabditis elegans)
Glycosphingolipid transport (Canis familiaris)
Glycosphingolipid transport (Danio rerio)
Glycosphingolipid transport (Drosophila melanogaster)
Glycosphingolipid transport (Gallus gallus)
Glycosphingolipid transport (Mus musculus)
Glycosphingolipid transport (Plasmodium falciparum)
Glycosphingolipid transport (Rattus norvegicus)
Glycosphingolipid transport (Saccharomyces cerevisiae)
Glycosphingolipid transport (Schizosaccharomyces pombe)
Glycosphingolipid transport (Sus scrofa)
Glycosphingolipid transport (Xenopus tropicalis)
Authored
Stephan, R (2023-10-05)
Reviewed
D'Eustachio, P (2023-10-24)
Created
Stephan, R (2023-10-05)
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