Reactome | VWF Y1584C multimer [extracellular region]

VWF Y1584C multimer [extracellular region]

Stable Identifier

R-HSA-9844293

Type

Complex

Species

Homo sapiens

Compartment

extracellular region

Synonyms

VWF Y1584C (764-2813) multimer, von Willibrand factor multimer

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Diseases of hemostasis (Homo sapiens)
  - Defects of platelet adhesion to exposed collagen (Homo sapiens)
    - Enhanced cleavage of VWF variant by ADAMTS13 (Homo sapiens)
      - ADAMTS13 cleaves VWF variant multimer (Homo sapiens)
        
        Collagen type I fibril:VWF variant multimer [extracellular region] (Homo sapiens)
        
        VWF variants with increased susceptibility to proteolysis [extracellular region] (Homo sapiens)
        
        VWF Y1584C multimer [extracellular region] (Homo sapiens)

Participants

components

x 50 VWF Y1584C (764-2813) [extracellular region] (Homo sapiens)

Participates

as a member of

VWF variants with increased susceptibility to proteolysis [extracellular region] (Homo sapiens)

Disease

Name	Identifier	Synonyms
blood platelet disease	DOID:2218	platelet disorder, Thrombocytopathy

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