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L1HS [nucleoplasm]
Stable Identifier
R-HSA-9843489
Type
Genes and Transcripts [GenomeEncodedEntity]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Regulation of endogenous retroelements (Homo sapiens)
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex (Homo sapiens)
MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
L1HS [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
L1HS [nucleoplasm] (Homo sapiens)
MPHOSPH8 of the HUSH complex bound to retroelement chromatin binds ZCCHC8 of the NEXT complex (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
L1HS [nucleoplasm] (Homo sapiens)
NEXT complex:HUSH complex:L1HS:L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
L1HS [nucleoplasm] (Homo sapiens)
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Homo sapiens)
me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
L1HS [nucleoplasm] (Homo sapiens)
me3-K16-ATF7IP:SETDB1 and MORC2 bind MPHOSPH8 (MPP8) in HUSH complex:L1HS,L1PA2,3 heterochromatin (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
L1HS [nucleoplasm] (Homo sapiens)
me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3:Nucleosome with H2K9me3 [nucleoplasm] (Homo sapiens)
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
L1HS [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
7877164
Ancestral, mammalian-wide subfamilies of LINE-1 repetitive sequences
Tóth, G
,
Riggs, AD
,
Jurka, J
,
Smit, AF
J Mol Biol
1995
29308093
Human transposable elements in Repbase: genomic footprints from fish to humans
Kojima, KK
Mob DNA
2018
Participates
as a member of
L1HS,L1PA2,3 [nucleoplasm] (Homo sapiens)
Cross References
NCBI Nucleotide
X58075
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