Reactome | Mature HEXB [lysosomal lumen]

Stable Identifier

R-HSA-9842389

Type

Complex

Species

Homo sapiens

Compartment

lysosomal lumen

Synonyms

Mature beta-hexosaminidase subunit beta

Locations in the PathwayBrowser

Expand all

Literature References

PubMed ID	Title	Journal	Year
2965147	Proteolytic processing of pro-alpha and pro-beta precursors from human beta-hexosaminidase. Generation of the mature alpha and beta a beta b subunits Mahuran, DJ, Neote, K, Klavins, MH, Leung, A, Gravel, RA	J Biol Chem	1988
6230116	The beta 2 subunit of human placenta hexosaminidase (Hex) A and B is a non-random association of the two polypeptides beta a and beta b O'Dowd, B, Mahuran, D, Lowden, JA	Biosci Rep	1984
12662933	Crystal structure of human beta-hexosaminidase B: understanding the molecular basis of Sandhoff and Tay-Sachs disease Mark, BL, Mahuran, DJ, Cherney, MM, Zhao, D, Knapp, S, James, MN	J Mol Biol	2003

Participants

components

Participates

as a component of

Inferred To

Mature HEXB [lysosomal lumen] (Bos taurus)

Mature HEXB [lysosomal lumen] (Gallus gallus)

Mature HEXB [lysosomal lumen] (Mus musculus)

Mature HEXB [lysosomal lumen] (Sus scrofa)