GM1 localizes to ILV membrane

Stable Identifier
R-HSA-9840579
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
endosome membrane, multivesicular body, internal vesicle membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
GM1 localizes to ILV membrane
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
As the late endosome becomes a lysosome, inward budding of the lysosomal membrane creates intralysosomal luminal vesicles (ILV) that carry lipids, including GM1, on their outside (reviewed by Sandhoff & Sandhoff, 2018).
Literature References
PubMed ID Title Journal Year
29802621 Emerging concepts of ganglioside metabolism

Sandhoff, R, Sandhoff, K

FEBS Lett 2018
Participants
Input
Output
Participates
as an event of
Authored
Stephan, R  (2023-07-19)
Reviewed
D'Eustachio, P  (2023-08-17)
Created
Stephan, R  (2023-07-20)
Cite Us!