TGFBR3 regulates activin signaling

Stable Identifier
R-HSA-9839406
Type
Pathway
Species
Homo sapiens
ReviewStatus
3/5
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TGFBR3 regulates activin signaling
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This subpathway describes the regulation of activin signaling by TGFBR3. TGFBR3 binds with Inhibin A, which is also a ligand for TGFBR3 and inhibits activin/BMP signaling by binding competititively to ACVR2A receptor and BMPRII (Esparza-Lopez et al., 2001, Lewis et al., 2000, Wiater et al., 2003).
Literature References
PubMed ID Title Journal Year
11278442 Ligand binding and functional properties of betaglycan, a co-receptor of the transforming growth factor-beta superfamily. Specialized binding regions for transforming growth factor-beta and inhibin A

Vilchis-Landeros, MM, López-Casillas, F, Montiel, JL, Esparza-Lopez, J, Okadome, T, Miyazono, K

J Biol Chem 2001
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Orthologous Events
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Authored
Tiwari, K  (2023-07-25)
Created
Tiwari, K  (2023-07-05)
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