TGFBR3 regulates TGF-beta signaling

Stable Identifier
R-HSA-9839389
Type
Pathway
Species
Homo sapiens
ReviewStatus
3/5
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TGFBR3 regulates TGF-beta signaling
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This subpathway describes the activation of TGFBR3 by TGF ligands and the subsequent regulation of TGF signaling by TGFBR3 (López‑Casillas et al.,1991,López‑Casillas et al.,1994, Blobe et al.,2001)
Literature References
PubMed ID Title Journal Year
8391934 Betaglycan presents ligand to the TGF beta signaling receptor

Wrana, JL, López-Casillas, F, Massagué, J

Cell 1993
8106553 Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites

Payne, HM, López-Casillas, F, Massagué, J, Andres, JL

J Cell Biol 1994
11323414 Functional roles for the cytoplasmic domain of the type III transforming growth factor beta receptor in regulating transforming growth factor beta signaling

Lodish, HF, Schiemann, WP, Blobe, GC, Pepin, MC, Moustakas, A, O'Connor-McCourt, MD, Beauchemin, M

J Biol Chem 2001
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Orthologous Events
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TGFBR3 regulates TGF-beta signaling (Xenopus tropicalis)
Cross References
BioModels Database
Authored
Tiwari, K  (2023-07-25)
Created
Tiwari, K  (2023-07-05)
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