Reactome | HELLS [nucleoplasm]

HELLS [nucleoplasm]

Stable Identifier

R-HSA-9839382

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Lymphoid-specific helicase ecNumber3.6.4.-/ecNumber, HELLS_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NRZ9 HELLS

Gene Names

HELLS, PASG, SMARCA6, Nbla10143

Chain

chain:1-838

Reference Genes

BioGPS Gene:3070 HELLS

COSMIC (genes):HELLS HELLS

CTD Gene:3070 HELLS

dbSNP Gene:3070 HELLS

ENSEMBL:ENSG00000119969 HELLS

HGNC:4861 HELLS

KEGG:hsa:3070 HELLS

Monarch:3070 HELLS

NCBI Gene:3070 HELLS

OMIM:603946 HELLS

UCSC:Q9NRZ9 HELLS

Reference Transcript

This entity regulates

Negatively

TGFBR3 transcription (Homo sapiens)

Cross References

OpenTargets

ENSG00000119969

ENSEMBL

ENSP00000513942, ENSP00000377609, ENSP00000360383, ENSP00000513943, ENSP00000513967, ENST00000348459, ENST00000698830, ENST00000394045, ENST00000698675, ENSP00000409945, ENSP00000239027, ENST00000698800, ENST00000371332, ENSP00000513940, ENSG00000119969, ENST00000419900, ENST00000698799

HPA

ENSG00000119969-HELLS

GeneCards

HELLS

PRO

Q9NRZ9

Pharos - Targets

Q9NRZ9

Orphanet

HELLS

GlyGen

Q9NRZ9

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P01106 MYC	2	MYC [nucleoplasm] (R-HSA-188379) PolyUb-MYC [nucleoplasm] (R-HSA-6783169)	0.564	2
UniProt:O00716 E2F3	2	p-E2F3 [nucleoplasm] (R-HSA-187933) E2F3 [nucleoplasm] (R-HSA-68655)	0.499	2

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