TGFBR3 binding to ARRB1/2

Stable Identifier
R-HSA-9839378
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytoplasmic side of plasma membrane
ReviewStatus
3/5
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TGFBR3 binding to ARRB1/2
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The binding of b-arrestin 2 (ARBB2) to TGFBR3 is triggered yb phosphorylation of the TBFBR3 at its cytoplasmic domain (likely at threonine 841) which is mediated by TGFBR2 receptors activated by TGFB1/2. (Chen et al.,2003)
Literature References
PubMed ID Title Journal Year
12958365 Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling

Chen, W, Frederick, JP, Wang, XF, Blobe, GC, Mo, J, Kirkbride, KC, Nelson, CD, How, T, Lefkowitz, RJ

Science 2003
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Authored
Tiwari, K  (2023-07-25)
Created
Tiwari, K  (2023-07-05)
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