AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane]

Stable Identifier
R-HSA-9838612
Type
Complex
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
14623864 Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia

Atorino, L, Silvestri, L, Koppen, M, Cassina, L, Ballabio, A, Marconi, R, Langer, T, Casari, G

J Cell Biol 2003
17101804 Variable and tissue-specific subunit composition of mitochondrial m-AAA protease complexes linked to hereditary spastic paraplegia

Koppen, M, Metodiev, MD, Casari, G, Rugarli, EI, Langer, T

Mol Cell Biol 2007
Participants
components
Participates
as an input of
as an output of
as a component of
Inferred To
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Bos taurus)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Caenorhabditis elegans)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Canis familiaris)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Danio rerio)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Dictyostelium discoideum)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Drosophila melanogaster)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Gallus gallus)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Mus musculus)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Plasmodium falciparum)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Rattus norvegicus)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Saccharomyces cerevisiae)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Schizosaccharomyces pombe)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Sus scrofa)
AFG3L2:Zn2+:SPG7:Zn2+ heterohexamer [mitochondrial inner membrane] (Xenopus tropicalis)
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