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ALAS1:heme [mitochondrial matrix]
Stable Identifier
R-HSA-9838300
Type
Complex
Species
Homo sapiens
Compartment
mitochondrial matrix
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Mitochondrial protein degradation (Homo sapiens)
CLPXP binds mitochondrial matrix proteins (Homo sapiens)
CLPXP:substrate protein (mitochondrial matrix) [mitochondrial matrix] (Homo sapiens)
Substrate of CLPXP (mitrochondrial matrix) [mitochondrial matrix] (Homo sapiens)
ALAS1:heme [mitochondrial matrix] (Homo sapiens)
Substrate of CLPXP (mitrochondrial matrix) [mitochondrial matrix] (Homo sapiens)
ALAS1:heme [mitochondrial matrix] (Homo sapiens)
CLPXP degrades mitochondrial matrix proteins (Homo sapiens)
CLPXP:substrate protein (mitochondrial matrix) [mitochondrial matrix] (Homo sapiens)
Substrate of CLPXP (mitrochondrial matrix) [mitochondrial matrix] (Homo sapiens)
ALAS1:heme [mitochondrial matrix] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
27496948
Novel Mechanisms for Heme-dependent Degradation of ALAS1 Protein as a Component of Negative Feedback Regulation of Heme Biosynthesis
Kubota, Y
,
Furuyama, K
,
Yamashita, R
,
Katoh, Y
,
Nomura, K
,
Kaneko, K
J Biol Chem
2016
Participants
components
ALAS1 [mitochondrial matrix]
(Homo sapiens)
heme [mitochondrial matrix]
Participates
as a member of
Substrate of CLPXP (mitrochondrial matrix) [mitochondrial matrix] (Homo sapiens)
Inferred To
ALAS1:heme [mitochondrial matrix]
(Bos taurus)
ALAS1:heme [mitochondrial matrix]
(Canis familiaris)
ALAS1:heme [mitochondrial matrix]
(Drosophila melanogaster)
ALAS1:heme [mitochondrial matrix]
(Mus musculus)
ALAS1:heme [mitochondrial matrix]
(Rattus norvegicus)
ALAS1:heme [mitochondrial matrix]
(Sus scrofa)
ALAS1:heme [mitochondrial matrix]
(Xenopus tropicalis)
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