hRSV A enters host cell through membrane fusion

Stable Identifier
R-HSA-9837543
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Human respiratory syncytial virus A
Compartment
plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
hRSV A enters host cell through membrane fusion
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
After attachment, the ribonucleocapsid of the human respiratory syncytial virus (RSV) A , the virus enters the host cell through release of the ribonucleocapsid into the cytosol. RSV entry into the host cell by direct fusion of the viral membrane and the plasma membrane is a route consistent with the established entry of the family Paramyxoviridae, closely related to the RSV's Pneumoviridae family, and is supported by studies that showed RSV host cell entry to be pH-independent and insensitive to lysosome acidification (Srinivasakumar et al. 1991; Kahn et al. 1999).
Literature References
Participants
Input
Output
Participates
as an event of
Disease
Cross References
Mondo
Authored
Orlic-Milacic, M  (2023-06-16)
Reviewed
Bergeron, HC  (2023-11-03)
Created
Orlic-Milacic, M  (2023-06-16)
Cite Us!