Reactome | PNPT1 [mitochondrial matrix]

PNPT1 [mitochondrial matrix]

Stable Identifier

R-HSA-9836559

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

fullName evidence="24"Polyribonucleotide nucleotidyltransferase 1, mitochondrial ecNumber evidence="14"2.7.7.8/ecNumber, PNPT1_HUMAN

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External Reference Information

External Reference

UniProt:Q8TCS8 PNPT1

Gene Names

PNPT1, PNPASE

Chain

transit peptide:1-45, chain:46-783

Reference Genes

BioGPS Gene:87178 PNPT1

COSMIC (genes):PNPT1 PNPT1

CTD Gene:87178 PNPT1

dbSNP Gene:87178 PNPT1

ENSEMBL:ENSG00000138035 PNPT1

ENSEMBL_homo_sapiens_GENE:ENSG00000138035.15 PNPT1

HGNC:23166 PNPT1

KEGG Gene (Homo sapiens):87178 PNPT1

Monarch:87178 PNPT1

NCBI Gene:87178 PNPT1

OMIM:610316 PNPT1

UCSC:Q8TCS8 PNPT1

Reference Transcript

RefSeq:NM_033109.4 PNPT1

Other Identifiers

11734725_a_at

11734726_x_at

16897797

225291_PM_at

225291_at

2553971

2553972

2553974

2553975

2553976

2553977

2553979

2553981

2553982

2553983

2553984

2553985

2553986

2553989

2553990

2553991

2553993

2553995

2553997

2553998

2553999

2554000

2554001

2554002

2554003

2554005

2554006

2554007

2554008

2554009

2554011

2660859

2660861

2660926

64038_at

8052331

87178

A_19_P00326178

A_23_P154488

A_32_P76035

GE57033

GO:0000175

GO:0000957

GO:0000958

GO:0000962

GO:0000964

GO:0000965

GO:0003676

GO:0003723

GO:0003824

GO:0004518

GO:0004527

GO:0004654

GO:0005515

GO:0005737

GO:0005739

GO:0005758

GO:0005759

GO:0005783

GO:0005789

GO:0005829

GO:0005840

GO:0006091

GO:0006396

GO:0006397

GO:0006401

GO:0006402

GO:0007005

GO:0008266

GO:0016020

GO:0016071

GO:0016740

GO:0016779

GO:0016787

GO:0034046

GO:0034599

GO:0035198

GO:0035458

GO:0035927

GO:0035928

GO:0042802

GO:0043226

GO:0043457

GO:0045025

GO:0045926

GO:0048856

GO:0051260

GO:0051591

GO:0051726

GO:0055085

GO:0060416

GO:0061014

GO:0065003

GO:0070207

GO:0071042

GO:0097222

GO:0097421

GO:0140053

GO:0140098

GO:1902494

GO:2000627

GO:2000772

HMNXSV003032745

Hs.24170.0.S1_3p_at

ILMN_1810608

ILMN_2051408

PH_hs_0018936

TC02001866.hg

Participates

as a component of

SUPV3L1:PNPT1 [mitochondrial matrix] (Homo sapiens)

Cross References

RefSeq

NP_149100.2

OpenTargets

ENSG00000138035

HPA

ENSG00000138035-PNPT1

GeneCards

Q8TCS8

Ensembl

ENST00000415374, ENST00000447944, ENSP00000393953, ENSP00000400646, ENSG00000138035

PRO

Q8TCS8

Pharos - Targets

Q8TCS8

PDB

3U1K, 5ZF6

HMDB Protein

HMDBP01290

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8IWL3 HSCB	5	HSCB [mitochondrial matrix] (R-HSA-1299438) HSCB(1-30) [mitochondrial matrix] (R-HSA-8986120) HSCB(1-235) [mitochondrial inner membrane] (R-HSA-1299443) HSCB [mitochondrial inner membrane] (R-HSA-1299447) HSCB(1-235) [mitochondrial intermembrane space] (R-HSA-1299456)	0.547	2
UniProt:Q969Z0 TBRG4	1	TBRG4 [mitochondrial matrix] (R-HSA-9837166)	0.527	2
UniProt:Q15363 TMED2	5	TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-1911531) TMED2 [endoplasmic reticulum membrane] (R-HSA-5689480) TMED2 [ER to Golgi transport vesicle membrane] (R-HSA-5689847) TMED2 [transport vesicle] (R-HSA-6808806) TMED2 [Golgi membrane] (R-HSA-6808804)	0.527	3