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TFAP2A binds TFAP2B
Stable Identifier
R-HSA-9836275
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Developmental Biology (Homo sapiens)
Gastrulation (Homo sapiens)
Specification of the neural plate border (Homo sapiens)
TFAP2A binds TFAP2B (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
TFAP2A binds TFAP2B through an interaction between a dimerization motif in the C-terminal region of each monomer (Bosher et al. 1996, and inferred from TFAP2A homodimers in Williams and Tjian 1991a, 1991b).
Literature References
PubMed ID
Title
Journal
Year
8895516
A family of AP-2 proteins regulates c-erbB-2 expression in mammary carcinoma
Williams, T
,
Totty, NF
,
Bosher, JM
,
Hsuan, JJ
,
Hurst, HC
Oncogene
1996
Participants
Input
TFAP2A [nucleoplasm]
(Homo sapiens)
TFAP2B [nucleoplasm]
(Homo sapiens)
Output
TFAP2A:TFAP2B [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Specification of the neural plate border (Homo sapiens)
Orthologous Events
TFAP2A binds TFAP2B (Bos taurus)
TFAP2A binds TFAP2B (Caenorhabditis elegans)
TFAP2A binds TFAP2B (Canis familiaris)
TFAP2A binds TFAP2B (Drosophila melanogaster)
TFAP2A binds TFAP2B (Gallus gallus)
TFAP2A binds TFAP2B (Mus musculus)
TFAP2A binds TFAP2B (Rattus norvegicus)
TFAP2A binds TFAP2B (Sus scrofa)
TFAP2A binds TFAP2B (Xenopus tropicalis)
Authored
May, B (2023-05-24)
Reviewed
Patthey, C (2023-10-28)
Gunhaga, L (2023-10-28)
Created
May, B (2023-05-24)
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