Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane]
Stable Identifier
R-HSA-983387
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
1C07_HUMAN, HLA-C
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Homo sapiens)
Expression of peptide bound class I MHC on cell surface (Homo sapiens)
Antigen peptide bound class I MHC [Golgi membrane] (Homo sapiens)
monoglucosylated MHC class I HC [Golgi membrane] (Homo sapiens)
Class I MHC heavy chain (MHC HC) [Golgi membrane] (Homo sapiens)
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane] (Homo sapiens)
Journey of cargo through Golgi complex (Homo sapiens)
Antigen peptide bound class I MHC [Golgi membrane] (Homo sapiens)
monoglucosylated MHC class I HC [Golgi membrane] (Homo sapiens)
Class I MHC heavy chain (MHC HC) [Golgi membrane] (Homo sapiens)
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P10321 HLA-C
Gene Names
HLA-C, HLAC
Chain
signal peptide:1-24, chain:25-366
Reference Genes
BioGPS Gene:3107 HLA-C
COSMIC (genes):HLA-C HLA-C
CTD Gene:3107 HLA-C
dbSNP Gene:3107 HLA-C
ENSEMBL:ENSG00000204525 HLA-C
ENSEMBL_homo_sapiens_GENE:ENSG00000204525.18 HLA-C
HGNC:4933 HLA-C
KEGG Gene (Homo sapiens):3107 HLA-C
Monarch:3107 HLA-C
NCBI Gene:3107 HLA-C
UCSC:P10321 HLA-C
Reference Transcript
RefSeq:NM_002117.5 HLA-C
Other Identifiers
11715316_x_at
17017126
17029003
216526_PM_x_at
216526_x_at
2900985
2900990
2901160
2901186
2901190
2901216
2901249
2901470
2901471
2901631
2948892
2948893
2948894
2948896
2948897
2948899
2948901
2948904
2948905
2948906
2948907
2948908
2948909
2948910
2948914
2948915
2948918
2948919
2948945
2948946
2948951
3107
8124901
8178489
A_24_P298409
A_33_P3330109
GO:0000139
GO:0001916
GO:0002250
GO:0002376
GO:0002474
GO:0002476
GO:0002486
GO:0005102
GO:0005515
GO:0005576
GO:0005615
GO:0005768
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0006955
GO:0009897
GO:0009986
GO:0012507
GO:0016020
GO:0019882
GO:0030667
GO:0030670
GO:0031410
GO:0031901
GO:0042605
GO:0042612
GO:0043226
GO:0045087
GO:0046977
GO:0055038
GO:0070062
GO:0098542
GO:0098553
HMNXSV003026726
Hs.277477.2.S1_3p_x_at
ILMN_2150787
Participates
as a member of
Class I MHC heavy chain (MHC HC) [Golgi membrane] (Homo sapiens)
Other forms of this molecule
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [phagocytic vesicle membrane]
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [recycling endosome membrane]
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [early endosome membrane]
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [ER to Golgi transport vesicle membrane]
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [plasma membrane]
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [secretory granule membrane]
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane]
Inferred To
H2-M3 [Golgi membrane]
(Mus musculus)
H2-Q6 [Golgi membrane]
(Mus musculus)
RT1-M1-5 [Golgi membrane]
(Rattus norvegicus)
RT1-CE14 [Golgi membrane]
(Rattus norvegicus)
ENSRNOG00000069480 [Golgi membrane]
(Rattus norvegicus)
H2-M10.6 [Golgi membrane]
(Mus musculus)
BOLA-NC1 [Golgi membrane]
(Bos taurus)
Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane]
(Bos taurus)
Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane]
(Canis familiaris)
Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane]
(Danio rerio)
Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane]
(Gallus gallus)
Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane]
(Mus musculus)
Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane]
(Rattus norvegicus)
Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane]
(Sus scrofa)
SLA-8 [Golgi membrane]
(Sus scrofa)
H2-M2 [Golgi membrane]
(Mus musculus)
RT1-M1-4 [Golgi membrane]
(Rattus norvegicus)
DLA-64 [Golgi membrane]
(Canis familiaris)
RT1-M1-2 [Golgi membrane]
(Rattus norvegicus)
hlazel [Golgi membrane]
(Danio rerio)
dZ63M10.1 [Golgi membrane]
(Danio rerio)
DLA88 [Golgi membrane]
(Canis familiaris)
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane]
(Bos taurus)
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane]
(Canis familiaris)
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane]
(Danio rerio)
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane]
(Gallus gallus)
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane]
(Mus musculus)
HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [Golgi membrane]
(Sus scrofa)
DLA-12 [Golgi membrane]
(Canis familiaris)
RT1-N3 [Golgi membrane]
(Rattus norvegicus)
H2-M10.1 [Golgi membrane]
(Mus musculus)
SLA-7 [Golgi membrane]
(Sus scrofa)
H2-M1 [Golgi membrane]
(Mus musculus)
RT1-M2 [Golgi membrane]
(Rattus norvegicus)
BOLA [Golgi membrane]
(Bos taurus)
H2-M9 [Golgi membrane]
(Mus musculus)
dZ63M10.3 [Golgi membrane]
(Danio rerio)
CH73-211L2.2 [Golgi membrane]
(Danio rerio)
RT1-M5 [Golgi membrane]
(Rattus norvegicus)
RT1-CE16 [Golgi membrane]
(Rattus norvegicus)
RT1-M10-1 [Golgi membrane]
(Rattus norvegicus)
H2-T22 [Golgi membrane]
(Mus musculus)
H2-M10.4 [Golgi membrane]
(Mus musculus)
H2-K1 [Golgi membrane]
(Mus musculus)
ENSRNOG00000064836 [Golgi membrane]
(Rattus norvegicus)
UBA*01 [Golgi membrane]
(Danio rerio)
RT1-S3 [Golgi membrane]
(Rattus norvegicus)
LOC102546590 [Golgi membrane]
(Rattus norvegicus)
LOC616942 [Golgi membrane]
(Bos taurus)
RT1-M3-1 [Golgi membrane]
(Rattus norvegicus)
RT1-CE2 [Golgi membrane]
(Rattus norvegicus)
H2-M10.3 [Golgi membrane]
(Mus musculus)
BoLA [Golgi membrane]
(Bos taurus)
LOC120093125 [Golgi membrane]
(Rattus norvegicus)
H2-Q1 [Golgi membrane]
(Mus musculus)
RT1-CE1 [Golgi membrane]
(Rattus norvegicus)
H2-M11 [Golgi membrane]
(Mus musculus)
AABR07044308.2 [Golgi membrane]
(Rattus norvegicus)
H2-M10.2 [Golgi membrane]
(Mus musculus)
H2-M5 [Golgi membrane]
(Mus musculus)
H2-D1 [Golgi membrane]
(Mus musculus)
JSP.1 [Golgi membrane]
(Bos taurus)
BF1 [Golgi membrane]
(Gallus gallus)
H2-Q2 [Golgi membrane]
(Mus musculus)
H2-M10.5 [Golgi membrane]
(Mus musculus)
H2-Q10 [Golgi membrane]
(Mus musculus)
H2-Q4 [Golgi membrane]
(Mus musculus)
H2-T23 [Golgi membrane]
(Mus musculus)
RT1-A1 [Golgi membrane]
(Rattus norvegicus)
AABR07044362.1 [Golgi membrane]
(Rattus norvegicus)
DLA-79 [Golgi membrane]
(Canis familiaris)
H2-Q7 [Golgi membrane]
(Mus musculus)
H2-T3 [Golgi membrane]
(Mus musculus)
SLA-6 [Golgi membrane]
(Sus scrofa)
Cross References
RefSeq
NP_002108.4
OpenTargets
ENSG00000204525
GeneCards
P10321
HPA
ENSG00000204525-HLA-C
Ensembl
ENSP00000365402
,
ENSG00000204525
,
ENST00000376228
PRO
P10321
Pharos - Targets
P10321
PDB
4NT6
,
5W69
,
3BZF
,
5VGD
,
1IM9
,
1EFX
,
1QQD
,
5VGE
,
6PAG
,
5W6A
,
6JTO
,
5W67
,
6PA1
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P61769 B2M
11
B2M(21-119) [early endosome membrane]
(R-HSA-182298)
B2M(21-119) [phagocytic vesicle membrane]
(R-HSA-1236891)
B2M(21-119) [recycling endosome membrane]
(R-HSA-8863880)
B2M(21-119) [early endosome lumen]
(R-HSA-1236827)
B2M(21-119) [Golgi membrane]
(R-HSA-983403)
B2M(21-119) [ER to Golgi transport vesicle membrane]
(R-HSA-983378)
B2M(21-119) [specific granule lumen]
(R-HSA-6806144)
B2M(21-119) [extracellular region]
(R-HSA-1302721)
B2M(21-119) [tertiary granule lumen]
(R-HSA-6800179)
B2M(21-119) [endoplasmic reticulum lumen]
(R-HSA-983063)
B2M(21-119) [plasma membrane]
(R-HSA-167743)
0.835
9
UniProt:P43626 KIR2DL1
1
KIR2DL1 [plasma membrane]
(R-HSA-199538)
0.792
15
UniProt:Q9UI95 MAD2L2
1
MAD2L2 [nucleoplasm]
(R-HSA-59092)
0.527
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text