Reactome | OTX2 [nucleoplasm]

OTX2 [nucleoplasm]

Stable Identifier

R-HSA-9832936

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Homeobox protein OTX2, OTX2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P32243 OTX2

Gene Names

OTX2

Chain

chain:1-289

Reference Genes

BioGPS Gene:5015 OTX2

COSMIC (genes):OTX2 OTX2

CTD Gene:5015 OTX2

dbSNP Gene:5015 OTX2

ENSEMBL:ENSG00000165588 OTX2

HGNC:8522 OTX2

KEGG:hsa:5015 OTX2

Monarch:5015 OTX2

NCBI Gene:5015 OTX2

OMIM:600037 OTX2

UCSC:P32243 OTX2

Reference Transcript

Participates

as an output of

Expression of OTX2 in anterior neural plate (Homo sapiens)

This entity regulates

Negatively

Expression of GBX2 in posterior neural plate (Homo sapiens)

Cross References

RefSeq

NP_068374.1, NP_758840.1, NP_001257454.1, NP_001257453.1, NP_001257452.1

OpenTargets

ENSG00000165588

ENSEMBL

ENST00000673035, ENST00000408990, ENST00000672264, ENSP00000500061, ENSP00000508798, ENSP00000451357, ENSP00000500595, ENSP00000452336, ENSP00000343819, ENSP00000500115, ENST00000339475, ENST00000685244, ENST00000554845, ENST00000555006, ENST00000673481, ENSP00000451272, ENST00000555804, ENSG00000165588, ENSP00000386185

HPA

ENSG00000165588-OTX2

GeneCards

OTX2

PRO

P32243

Pharos - Targets

P32243

GlyGen

P32243

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P54253 ATX1			0.553	2
UniProt:Q2Q067 Q2Q067			0.488	2

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