Expression of ZNF521 in anterior neural plate

Stable Identifier
R-HSA-9832834
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Expression of ZNF521 in anterior neural plate
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ZNF521 (ZFP521) is weakly expressed before gastrulation and then becomes strongly expressed in the epiblast, especially the prospective neuroectoderm (inferred from mouse embryos). After gastrulation, ZNF521 is expressed strongly in the anterior neural plate and anterior neural tube and more weakly in the posterior neural plate (inferred from mouse embryos). Deletion of Znf521 in mice causes behavioral abnormalities and reduced numbers of granular neurons and neural progenitors in the dentate gyrus and cerebellum (Ohkubo et al. 2014).
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
POU3F1:ZNF521 gene [nucleoplasm] (Homo sapiens)
Active Unit
POU3F1 [nucleoplasm]
Inferred From
Expression of Znf521 in anterior neural plate (Mus musculus)
Authored
May, B  (2023-04-09)
Reviewed
Kondoh, H  (2023-07-12)
Created
May, B  (2023-04-09)
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