HNF1B binds the HNF4A gene

Stable Identifier
R-HSA-9832665
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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HNF1B binds the HNF4A gene
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HNF1B binds the promoter of the HNF4A gene and activates expression in the distal region of the comma-shaped body and the proximal region of the S-shaped body (inferred from mouse homologs and embryos in Heliot et al. 2013). In mice, Hnf4a encodes a transcription factor that is required for proximal tubule development, probably by regulating proximal tubule-specific genes (Marable et al. 2018).
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Hnf1b binds the Hnf4a gene (Mus musculus)
Authored
May, B  (2023-04-04)
Created
May, B  (2023-04-05)
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