WT1 binds the PAX2 gene

Stable Identifier
R-HSA-9832334
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
3/5
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WT1 binds sites in the 5' untranslated region of the PAX2 gene and represses transcription (inferred from mouse homologs). In mouse embryos, repression of Pax2 by Wt1 is involved in podocyte specification in the proximal region of renal vesicles and later stages (Kreidberg et al. 1993).
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