Expression of IRX2 during nephron development

Stable Identifier
R-HSA-9832208
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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Expression of IRX2 during nephron development
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HNF1B bound to conserved sites between the IRX2 and IRX1 genes activates expression of IRX2 in the intermediate region of the S-shaped body during development of the nephron (inferred from mouse homologs in Heliot et al. 2013). In mice, loss of Hnf1b causes complete loss of Irx2 expression in the S-shaped body (Heliot et al. 2013).
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
HNF1B:IRX2 gene [nucleoplasm] (Homo sapiens)
Active Unit
HNF1B [nucleoplasm]
Inferred From
Expression of Irx2 during nephron development (Mus musculus)
Authored
May, B  (2023-03-28)
Created
May, B  (2023-03-29)
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