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Expression of IRX1 during nephron development
Stable Identifier
R-HSA-9832183
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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Developmental Biology (Homo sapiens)
Kidney development (Homo sapiens)
Nephron development (Homo sapiens)
Expression of IRX1 during nephron development (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
IRX1 is expressed in the intermediate region of the S-shaped body during nephron development (inferred from mouse embryos in Yu et al. 2012, Heliot et al. 2013, Massa et al. 2013). HNF1B binds near the IRX1 gene to activate expression (inferred from mouse homologs in Heliot et al. 2013, Massa et al. 2013).
Participants
Input
IRX1 gene [nucleoplasm]
(Homo sapiens)
Output
IRX1 [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Nephron development (Homo sapiens)
This event is regulated
Positively by
Regulator
HNF1B:IRX1 gene [nucleoplasm]
(Homo sapiens)
Active Unit
HNF1B [nucleoplasm]
Inferred From
Expression of Irx1 during nephron development (Mus musculus)
Authored
May, B (2023-03-28)
Created
May, B (2023-03-29)
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