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monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane]
Stable Identifier
R-HSA-983120
Type
Complex
Species
Homo sapiens
Compartment
integral component of lumenal side of endoplasmic reticulum membrane
Synonyms
(Glc)1(Man)9(GlcNAc)2-MHC class I heavy chain
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
Capturing cargo and formation of prebudding complex (Homo sapiens)
8:class I MHC:BECN1 complex [endoplasmic reticulum membrane] (Homo sapiens)
8:antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
SARS-CoV-2 8 binds class I MHC (Homo sapiens)
8:antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
SARS-CoV-2 8:class I MHC binds BECN1 (Homo sapiens)
8:antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
8:class I MHC:BECN1 complex [endoplasmic reticulum membrane] (Homo sapiens)
8:antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Homo sapiens)
Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Budding of COPII coated vesicle (Homo sapiens)
COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Capturing cargo and formation of prebudding complex (Homo sapiens)
8:class I MHC:BECN1 complex [endoplasmic reticulum membrane] (Homo sapiens)
8:antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex (Homo sapiens)
Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Homo sapiens)
MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Homo sapiens)
MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Formation of peptide loading complex (PLC) (Homo sapiens)
MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Homo sapiens)
MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Interaction of Erp57 with MHC class I HC (Homo sapiens)
MHC class I HC:Calnexin/BiP:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Interaction of beta-2-microglobulin (B2M) chain with class I HC (Homo sapiens)
MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC class I HC:Calnexin/BiP:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Loading of antigenic peptides on to class I MHC (Homo sapiens)
Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Homo sapiens)
MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Homo sapiens)
MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Homo sapiens)
MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Homo sapiens)
COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Transport of MHC heterotrimer to ER exit site (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Participants
components
(Glc)1 (GlcNAc)2 (Man)9 [endoplasmic reticulum lumen]
Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane]
(Homo sapiens)
Participates
as an input of
Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Homo sapiens)
as a component of
monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Antigen peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)
Inferred To
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane]
(Bos taurus)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane]
(Canis familiaris)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane]
(Danio rerio)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane]
(Gallus gallus)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane]
(Mus musculus)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane]
(Rattus norvegicus)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane]
(Sus scrofa)
monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane]
(Xenopus tropicalis)
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