Reactome | SIX2 [nucleoplasm]

SIX2 [nucleoplasm]

Stable Identifier

R-HSA-9831037

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Homeobox protein SIX2, SIX2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9NPC8 SIX2

Gene Names

SIX2

Chain

chain:1-291

Reference Genes

BioGPS Gene:10736 SIX2

COSMIC (genes):SIX2 SIX2

CTD Gene:10736 SIX2

dbSNP Gene:10736 SIX2

ENSEMBL:ENSG00000170577 SIX2

HGNC:10888 SIX2

KEGG:hsa:10736 SIX2

Monarch:10736 SIX2

NCBI Gene:10736 SIX2

OMIM:604994 SIX2

UCSC:Q9NPC8 SIX2

Reference Transcript

RefSeq:NM_016932.4 SIX2

Other Identifiers

10736

11725907_at

16897159

206510_PM_at

206510_at

206511_PM_s_at

206511_s_at

2551229

2551230

2551231

2551232

2551233

2551236

2551238

2551239

2551240

8051949

89148_at

ADDON002693.hg

A_23_P28120

GE87568

GO:0000785

GO:0000978

GO:0000981

GO:0001228

GO:0001656

GO:0001822

GO:0002062

GO:0003337

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005667

GO:0006355

GO:0006357

GO:0006606

GO:0006886

GO:0006913

GO:0007501

GO:0008283

GO:0009653

GO:0009948

GO:0016477

GO:0030154

GO:0030278

GO:0030855

GO:0030857

GO:0032330

GO:0042474

GO:0043226

GO:0043565

GO:0044877

GO:0045944

GO:0048557

GO:0048701

GO:0048704

GO:0048856

GO:0048870

GO:0072006

GO:0072028

GO:0072038

GO:0072137

GO:0072161

GO:0090189

GO:0097168

GO:0140110

GO:1902732

GO:1990837

HMNXSV003039883

ILMN_1663772

PH_hs_0005664

TC02001804.hg

g13242164_3p_at

g8394273_3p_a_at

Participates

as an output of

Expression of SIX2 in metanephric mesenchyme (Homo sapiens)

Cross References

RefSeq

NP_058628.3

ENSEMBL

ENSP00000304502, ENST00000303077

OpenTargets

ENSG00000170577

HPA

ENSG00000170577-SIX2

PRO

Q9NPC8

Pharos - Targets

Q9NPC8

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q99502 EYA1	2	EYA1 [nucleoplasm] (R-HSA-5683625) p-EYA1 [nucleoplasm] (R-HSA-5683951)	0.643	3
UniProt:Q04726-4 TLE3			0.556	3
UniProt:Q8N3C7 CLIP4			0.556	3
UniProt:Q08117-2 TLE5			0.556	3
UniProt:O00167 EYA2	2	p-EYA2 [nucleoplasm] (R-HSA-5683954) EYA2 [nucleoplasm] (R-HSA-5683621)	0.527	2
UniProt:Q8IYQ7 THNS1			0.527	2
UniProt:Q2NKX8 ERCC6L	1	ERCC6L [cytosol] (R-HSA-376250)	0.527	3
UniProt:Q15139 PRKD1	1	PRKD1 [cytosol] (R-HSA-58210)	0.527	2
UniProt:Q9Y3E7 CHMP3	2	CHMP3 [endosome membrane] (R-HSA-9631191) CHMP3 [cytosol] (R-HSA-917722)	0.527	2
UniProt:Q9BT73 PSMG3	1	PSMG3 [cytosol] (R-HSA-9908033)	0.527	3
UniProt:Q14974 KPNB1	5	KPNB1 [cytosol] (R-HSA-180733) KPNB1 [nucleoplasm] (R-HSA-180714) KPNB1 [specific granule lumen] (R-HSA-6799646) KPNB1 [extracellular region] (R-HSA-6806306) KPNB1 [ficolin-1-rich granule lumen] (R-HSA-6800978)	0.527	3
UniProt:Q7Z5W3 BCDIN3D	1	BCDIN3D [cytosol] (R-HSA-5578737)	0.527	2
UniProt:O43633 CHMP2A	2	CHMP2A [cytosol] (R-HSA-917734) CHMP2A [endosome membrane] (R-HSA-9631172)	0.527	2
UniProt:Q9HD42 CHMP1A	1	CHMP1A [cytosol] (R-HSA-917721)	0.527	2
UniProt:Q04206-1 RELA			0.508	2

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