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ERAP2 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-983097
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
Endoplasmic reticulum aminopeptidase 2, ERAP2_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Homo sapiens)
Trimming of peptides in ER (Homo sapiens)
ERAP1/2 [endoplasmic reticulum lumen] (Homo sapiens)
ERAP2 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6P179 ERAP2
Gene Names
ERAP2, LRAP
Chain
chain:1-960
Reference Genes
BioGPS Gene:64167 ERAP2
COSMIC (genes):ERAP2 ERAP2
CTD Gene:64167 ERAP2
dbSNP Gene:64167 ERAP2
ENSEMBL:ENSG00000164308 ERAP2
HGNC:29499 ERAP2
KEGG:hsa:64167 ERAP2
Monarch:64167 ERAP2
NCBI Gene:64167 ERAP2
OMIM:609497 ERAP2
UCSC:Q6P179 ERAP2
Reference Transcript
RefSeq:NM_022350.4 ERAP2
RefSeq:NM_001329229.1 ERAP2
RefSeq:NM_001130140.2 ERAP2
RefSeq:NM_001329233.1 ERAP2
Other Identifiers
11722573_a_at
11745601_a_at
11747137_x_at
1554272_PM_at
1554272_at
1554273_PM_a_at
1554273_a_at
16987531
219759_3p_at
219759_PM_at
219759_at
227462_PM_at
227462_at
235104_PM_at
235104_at
2821367
2821368
2821369
2821370
2821371
2821372
2821373
2821374
2821375
2821376
2821377
2821378
2821379
2821382
2821383
2821384
2821385
2821387
2821388
2821389
2821390
2821392
2821393
2821394
2821399
2821400
2821401
2821402
2821403
2821404
2821406
2821407
2821408
2821409
2821410
2821411
2821412
44792_s_at
60854_at
64167
8107044
81089_at
81092_g_at
82982_at
88809_at
A_14_P100960
A_14_P121724
A_23_P30243
A_24_P342171
GE62893
GO:0002250
GO:0002376
GO:0002474
GO:0003824
GO:0004175
GO:0004177
GO:0005515
GO:0005615
GO:0005737
GO:0005783
GO:0005788
GO:0005789
GO:0006508
GO:0008217
GO:0008237
GO:0008270
GO:0016020
GO:0016787
GO:0019885
GO:0042277
GO:0043171
GO:0043226
GO:0046872
GO:0070006
GO:0140096
HMNXSV003010535
Hs.124764.0.A1_3p_at
Hs.23054.0.A1_3p_at
Hs2.280380.3.S1_3p_at
Hs2.280380.3.S1_3p_x_at
ILMN_1743145
ILMN_2123312
PH_hs_0024235
TC05000471.hg
g11641260_3p_x_at
Participates
as a member of
ERAP1/2 [endoplasmic reticulum lumen] (Homo sapiens)
Inferred To
Dmel\CG6071 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
Homologues of ERAP2 [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
Homologues of ERAP2 [endoplasmic reticulum lumen]
(Dictyostelium discoideum)
Homologues of ERAP2 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
Dmel\CG40470 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
ERAP2 [endoplasmic reticulum lumen]
(Bos taurus)
ERAP2 [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
ERAP2 [endoplasmic reticulum lumen]
(Dictyostelium discoideum)
ERAP2 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
ERAP2 [endoplasmic reticulum lumen]
(Sus scrofa)
Dmel\CG4467 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
pepCG2111 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001316158.1
,
NP_001123612.1
,
NP_071745.1
,
NP_001316162.1
Guide to Pharmacology - Targets
1567
OpenTargets
ENSG00000164308
ENSEMBL
ENSP00000369235
,
ENSP00000400376
,
ENST00000437043
,
ENSP00000421175
,
ENST00000510373
,
ENSP00000425758
,
ENSP00000421849
,
ENST00000510309
,
ENST00000379904
,
ENST00000513084
HPA
ENSG00000164308-ERAP2
ZINC - Substances
ERAP2_HUMAN
ZINC target
Q6P179
PRO
Q6P179
Pharos - Targets
Q6P179
GlyGen
Q6P179
ZINC - Predictions - Purchasable
ERAP2_HUMAN
PDB
7PFS
,
7SH0
,
7NUP
,
4JBS
,
5J6S
,
3SE6
,
7NSK
,
5CU5
,
7P7P
,
4E36
,
5K1V
,
5AB0
,
5AB2
,
6EA4
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