Expression of ID4 in the nephric duct

Stable Identifier
R-HSA-9830372
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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Expression of ID4 in the nephric duct
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The Inhibitor of DNA-binding 4 (ID4) gene is expressed in the developing nephric duct (inferred from the mouse homolog). In mouse embryos, Pax2 and Gata3 activate expression of Id4 but it is unknown if the regulation is due to direct binding of the factors to the Id4 gene (Boualia et al. 2013). ID4 appears to be involved in regulating stem cell survival and differentiation (reviewed in Patel et al. 2015).
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
GATA3 [nucleoplasm] (Homo sapiens)
Regulator
PAX2 [nucleoplasm] (Homo sapiens)
Inferred From
Expression of Id4 in the nephric duct (Mus musculus)
Authored
May, B  (2023-03-08)
Created
May, B  (2023-03-09)
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