G mRNA is translated into membrane-bound G protein

Stable Identifier
R-HSA-9828716
Type
Reaction [omitted]
Species
Homo sapiens
Related Species
Human respiratory syncytial virus A
Compartment
cytosol
ReviewStatus
5/5
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G mRNA is translated into membrane-bound G protein
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Human respiratory syncytial virus (hRSV) glycoprotein (G) mRNA contains two initiation codons (AUG) (Roberts et al. 1994). When translation is started from the first AUG, the resulting G protein variant of 298 amino acids possesses a transmembrane domain (Roberts et al. 1994) and initially localizes to the endoplasmic reticulum (Ding et al. 1987). For review, please refer to Anderson et al. 2021.
Literature References
PubMed ID Title Journal Year
3113070 Expression and glycosylation of the respiratory syncytial virus G protein in Saccharomyces cerevisiae

Ding, MX, Wen, DZ, Schlesinger, MJ, Wertz, GW, Ball, LA

Virology 1987
8207828 The membrane-associated and secreted forms of the respiratory syncytial virus attachment glycoprotein G are synthesized from alternative initiation codons

Roberts, SR, Lichtenstein, D, Ball, LA, Wertz, GW

J Virol 1994
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Cross References
Mondo
Authored
Orlic-Milacic, M  (2023-02-16)
Reviewed
Bergeron, HC  (2023-11-03)
Created
Orlic-Milacic, M  (2023-02-16)
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